Mapping the Areas of the Brain Associated With Language in Children With Epilepsy - Tabular View

Home

Study Topics

Glossary


	Full Text View


	Tabular View


	Contacts and Locations


	No Study Results Posted


	Related Studies

Mapping the Areas of the Brain Associated With Language in Children With Epilepsy

This study has been completed.

Study NCT00001366. Last updated on March 3, 2008. Information provided by National Institutes of Health Clinical Center (CC)

This Tabular View shows the required WHO registration data elements as marked by ^†

Descriptive Information Fields
Brief Title ^†	Mapping the Areas of the Brain Associated With Language in Children With Epilepsy
Official Title ^†	MRI-Based Functional Language Mapping in Children With Epilepsy
Brief Summary	Researchers are interested in studying if magnetic resonance imaging (MRI) is practical for locating the areas of the brain associated with language in children with epilepsy. When a region of the brain is active, it uses more fuel in the form of oxygen and sugar (glucose). As the brain uses more fuel it produces more waste products, carbon dioxide and water. Blood carries fuel to the brain and waste products away from the brain. As brain activity increases blood flow to and from the area of activity increases also. Patients participating in the study will be asked to perform tasks designed to test language skills while undergoing an MRI to detect areas of the brain using oxygen and receiving blood flow.
Detailed Description	We propose to study the feasibility of utilizing MRI to perform functional mapping of language cortex in children with epilepsy. We will use 1.5 Tesla MRI to study cerebral blood flow and tissue oxygenation during cognitive activation tasks derived from previous adult studies.
Study Phase
Study Type ^†	Observational
Study Design ^†
Primary Outcome Measure ^†
Secondary Outcome Measure ^†
Condition ^†	Epilepsy Seizures
Intervention ^†
MEDLINE PMIDs	9109891, 9109900, 8598182
Links

Recruitment Information Fields
Recruitment Status ^†	Completed
Enrollment ^†	230
Start Date ^†	August 1993
Completion Date	September 2002
Eligibility Criteria ^†	Children aged 5-17 years. Partial epilepsy (localized). Ability to cooperate with task paradigms (IQ greater than 65). No cardiac pacemakers, cochlear implants, shrapnel, vascular clips, braces, or claustrophobia. No one with inability to cooperate with task paradigms.
Gender	Both
Ages
Accepts Healthy Volunteers	Yes
Contacts ^††
Location Countries ^†	United States

Administrative Information Fields
NCT ID ^†	NCT00001366
Organization ID	930191
Secondary IDs ^††	93-N-0191
Study Sponsor ^†	National Institute of Neurological Disorders and Stroke (NINDS)
Collaborators ^††
Investigators ^†
Information Provided By	National Institutes of Health Clinical Center (CC)
Verification Date	September 2002
First Received Date ^†	November 3, 1999
Last Updated Date	March 3, 2008

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.