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Brain Tissue Collection for Neuropathological Studies

This study is currently recruiting participants.
Study NCT00001260.   Last updated on July 18, 2008.   Information provided by National Institutes of Health Clinical Center (CC)

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Descriptive Information Fields
Brief Title  Brain Tissue Collection for Neuropathological Studies
Official Title  Brain Procurement for the Neuropathology Section, CBDB
Brief Summary

The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders.

This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders....

Detailed Description

The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish a coordinating program with the pathology departments of the Washington, D.C. and metropolitan area hospitals and local medical examiner's offices for the donation of brain tissue.

Study Phase
Study Type  Observational
Study Design 
Primary Outcome Measure 
Secondary Outcome Measure 
Condition  Bipolar Disorder
Depression
Anxiety Disorders
Schizophrenia
Tourette's Syndrome
Brain Diseases
Intervention 
MEDLINE PMIDs 17290303,   16618933,   15310849
Links NIH Clinical Center Detailed Web Page This link exits the ClinicalTrials.gov site
Recruitment Information Fields
Recruitment Status  Recruiting
Enrollment  2000
Start Date  May 1990
Completion Date
Eligibility Criteria 
  • INCLUSION CRITERIA:

Brain tissue is needed from individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. In addition, brains from normal individuals without a history of neuropsychiatric disease will be needed for controls.

Gender Both
Ages
Accepts Healthy Volunteers Yes
Contacts ††
Contact: Joel E. Kleinman, M.D.     (301) 402-7909     kleinmaj@intra.nimh.nih.gov    
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00001260
Organization ID 900142
Secondary IDs †† 90-M-0142
Study Sponsor  National Institute of Mental Health (NIMH)
Collaborators ††
Investigators 
Information Provided By National Institutes of Health Clinical Center (CC)
Verification Date March 2008
First Received Date  November 3, 1999
Last Updated Date July 18, 2008

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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