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| Descriptive Information Fields | |||||
| Brief Title † | Brain Tissue Collection for Neuropathological Studies | ||||
| Official Title † | Brain Procurement for the Neuropathology Section, CBDB | ||||
| Brief Summary | The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders. This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders.... |
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| Detailed Description | The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish a coordinating program with the pathology departments of the Washington, D.C. and metropolitan area hospitals and local medical examiner's offices for the donation of brain tissue. |
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| Study Phase | |||||
| Study Type † | Observational | ||||
| Study Design † | |||||
| Primary Outcome Measure † | |||||
| Secondary Outcome Measure † | |||||
| Condition † | Bipolar Disorder Depression Anxiety Disorders Schizophrenia Tourette's Syndrome Brain Diseases |
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| Intervention † | |||||
| MEDLINE PMIDs | 17290303, 16618933, 15310849 | ||||
| Links | NIH Clinical Center Detailed Web Page ![]() |
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| Recruitment Information Fields | |||||
| Recruitment Status † | Recruiting | ||||
| Enrollment † | 2000 | ||||
| Start Date † | May 1990 | ||||
| Completion Date | |||||
| Eligibility Criteria † |
Brain tissue is needed from individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. In addition, brains from normal individuals without a history of neuropsychiatric disease will be needed for controls. |
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| Gender | Both | ||||
| Ages | |||||
| Accepts Healthy Volunteers | Yes | ||||
| Contacts †† |
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| Location Countries † | United States | ||||
| Administrative Information Fields | |||||
| NCT ID † | NCT00001260 | ||||
| Organization ID | 900142 | ||||
| Secondary IDs †† | 90-M-0142 | ||||
| Study Sponsor † | National Institute of Mental Health (NIMH) | ||||
| Collaborators †† | |||||
| Investigators † | |||||
| Information Provided By | National Institutes of Health Clinical Center (CC) | ||||
| Verification Date | March 2008 | ||||
| First Received Date † | November 3, 1999 | ||||
| Last Updated Date | July 18, 2008 | ||||