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Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study has been completed.
Study NCT00001192   Information provided by National Institutes of Health Clinical Center (CC)
First Received: November 3, 1999   Last Updated: March 5, 2008   History of Changes

November 3, 1999
March 5, 2008
October 1983
 
 
 
Complete list of historical versions of study NCT00001192 on ClinicalTrials.gov Archive Site
 
 
 
Neuropsychological Evaluation of Psychiatric and Neurological Patients
Neuropsychological Evaluation of Psychiatric and Neurological Patients

This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.

The goals of this research study are to;

  1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
  2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.

Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.

 
Observational
 
  • Anxiety Disorder
  • Head Injury
  • Mood Disorder
  • Schizophrenia
  • Seizures
 
 
Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103.

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Completed
4300
December 2006
 
  • INCLUSION CRITERIA:

Patients.

Normal volunteers.

EXCLUSION CRITERIA:

Subjects over 95 years of age.

Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.

Both
up to 95 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States,   France,   Russian Federation
 
NCT00001192
 
830176, 83-M-0176
National Institute of Mental Health (NIMH)
 
 
National Institutes of Health Clinical Center (CC)
December 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP