Isoflurane at Subanesthetic Concentrations - 6 - Tabular View

Tracking Information

First Received Date ^ICMJE

September 20, 1999

Last Updated Date

June 23, 2005

Start Date ^ICMJE

January 1995

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Pain intensity, pain bothersomeness
Mood
Psychomotor performance
Pain quality

Original Primary Outcome Measures ^ICMJE

Same as current

Change History

Complete list of historical versions of study NCT00000254 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Isoflurane at Subanesthetic Concentrations - 6

Official Title ^ICMJE

Isoflurane at Subanesthetic Concentrations

Brief Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To test the hypothesis that isoflurane at subanesthetic concentrations does not reduce cold-water immersion pain in healthy volunteers.

Detailed Description

Study Phase

Phase II

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment

Condition ^ICMJE

Opioid-Related Disorders
Substance-Related Disorders

Intervention ^ICMJE

Drug: Nitrous oxide

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

Primary Completion Date

Eligibility Criteria ^ICMJE

Please contact site for information.

Gender

Male

Ages

21 Years to 34 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

United States

Administrative Information

NCT ID ^ICMJE

NCT00000254

Responsible Party

Study ID Numbers ^ICMJE

NIDA-08391-6, R01-08391-6

Study Sponsor ^ICMJE

National Institute on Drug Abuse (NIDA)

Collaborators ^ICMJE

University of Chicago

Investigators ^ICMJE

Principal Investigator:

James Zacny, Ph.D.

University of Chicago

Information Provided By

National Institute on Drug Abuse (NIDA)

Verification Date

March 1995

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP