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Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women

This study has been completed.
Study NCT00000108.   Last updated on June 23, 2005.   Information provided by National Center for Research Resources (NCRR)

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Descriptive Information Fields
Brief Title  Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women
Official Title 
Brief Summary

The purpose of this research is to find out whether training at different exercise intensities reduces the risk of developing cardiovascular disease (CVD) to a different extent. Heart attacks and stroke are the leading cause of death in older women. Reduced variability of the heart rate and increased dips and swings in blood pressure are risks factors that predict the chance of developing CVD as are increased levels of clotting protein fibrinogen and plasminogen activator inhibitor 1, and high levels of LDL-cholesterol (>160mg/dl). We will be measuring all of these risk factors and any changes in your body fat level before you start training and after 15 and 30 weeks of training in the form of walking. At the present time the effects of exercise intensity on these factors are not well understood. This study will add to the basic understanding of these issues and allow us to recommend to postmenopausal women optimal exercise intensities to lose body fat and reduce the risk of developing CVD.

Detailed Description
Study Phase
Study Type  Interventional
Study Design  Prevention, Randomized, Parallel Assignment
Primary Outcome Measure 
Secondary Outcome Measure 
Condition  Cardiovascular Diseases
Coronary Disease
Intervention  Behavioral: Exercise
MEDLINE PMIDs
Links
Recruitment Information Fields
Recruitment Status  Completed
Enrollment 
Start Date 
Completion Date
Eligibility Criteria 

Inclusion Criteria:

  • Postmenopausal and preferably on hormone replacement therapy
  • In good general health
  • Have a body mass index (BMI, weight in kg/height in m2) of between 25 and 40
  • Exercise less than 20 min/day two days a week
Gender Female
Ages 50 Years to 65 Years
Accepts Healthy Volunteers Yes
Contacts ††
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00000108
Organization ID NCRR-M01RR00042-1647
Secondary IDs †† M01RR00042
Study Sponsor  National Center for Research Resources (NCRR)
Collaborators ††
Investigators 
Information Provided By National Center for Research Resources (NCRR)
Verification Date December 2003
First Received Date  January 18, 2000
Last Updated Date June 23, 2005

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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