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Body Water Content in Cyanotic Congenital Heart Disease

This study has been completed.
Study NCT00000107.   Last updated on June 23, 2005.   Information provided by National Center for Research Resources (NCRR)

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Descriptive Information Fields
Brief Title  Body Water Content in Cyanotic Congenital Heart Disease
Official Title 
Brief Summary

Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.

Detailed Description
Study Phase
Study Type  Observational
Study Design  Natural History, Case Control
Primary Outcome Measure 
Secondary Outcome Measure 
Condition  Heart Defects, Congenital
Intervention 
MEDLINE PMIDs
Links
Recruitment Information Fields
Recruitment Status  Completed
Enrollment 
Start Date 
Completion Date
Eligibility Criteria 

Inclusion Criteria:

  • Resting blood pressure below 140/90
Gender Both
Ages 17 Years to 60 Years
Accepts Healthy Volunteers Yes
Contacts ††
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00000107
Organization ID NCRR-M01RR00109-0737
Secondary IDs †† M01RR00109
Study Sponsor  National Center for Research Resources (NCRR)
Collaborators ††
Investigators 
Information Provided By National Center for Research Resources (NCRR)
Verification Date December 2003
First Received Date  January 18, 2000
Last Updated Date June 23, 2005

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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