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A Randomized Trial of Unruptured Brain AVMs (ARUBA)

This study is currently recruiting participants.
Study NCT00389181.   Last updated on June 3, 2008.   Information provided by National Institute of Neurological Disorders and Stroke (NINDS)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00389181


Contacts
Contact: J. P. Mohr, MS, MD     212 305 8033     jpm10@columbia.edu    
Contact: Alan J. Moskowitz, MD     212-305-9100     ajm4@columbia.edu    

Locations
United States, Alabama
University of South Alabama, Stroke Center, 2451 Fillingim Street, Suite 10I     Recruiting
      Mobile, Alabama, United States, 36617-2238
      Contact: Richard Zweifler, M.D.     251-470-5801     rzweifle@usouthal.edu    
United States, Arizona
Barrow Neurological Institute, 350 West Thomas Road     Recruiting
      Phoenix, Arizona, United States, 85013
      Contact: Joseph Zabramski, M.D.     602-406-3465     joseph.zabramski@bnaneuro.net    
United States, California
University of California at Los Angeles, UCLA School of Medicine, 710 Westwood Plaza     Recruiting
      Los Angeles, California, United States, 90095-1769
      Contact: Jeffrey L. Saver, M.D.     310-794-6379     jsaver@ucla.edu    
University of California at San Francisco, 1001 Potrero Avenue- Rm 3C-38     Recruiting
      San Francisco, California, United States, 94110
      Contact: William Young, M.D.     415-206-8906     youngw@anesthesia.ucsf.edu    
United States, Illinois
Loyola University Stritch School of Medicine, Department of Neurology, 2160 S 1st Ave, Bldg 105/2700     Recruiting
      Maywood, Illinois, United States, 60153-3304
      Contact: Jose Biller, M.D.     708-216-2438     jbiller@lumc.edu    
United States, Iowa
University of Iowa Hospitals, Department of Neurology, 200 Hawkins Drive ,     Recruiting
      Iowa City, Iowa, United States, 52242-1009
      Contact: Harold P. Adams, Jr., M.D.     319-356-5796     harold-adams@uiowa.edu    
United States, Massachusetts
Boston University School of Medicine, 715 Albany St., Robinson Building B-605     Recruiting
      Boston, Massachusetts, United States, 02118-2526
      Contact: Carlos S. Kase, M.D.     617-638-5102     cskase@bu.edu    
United States, Michigan
Michigan Head and Spine Institute, Providence Hospital and Medical Center, 16001 West Nine Mile Road     Recruiting
      Southfield, Michigan, United States, 48075
      Contact: Richard D. Fessler, M.D.     877-784-3667     richard.fessler@providence-stjohnhealth.org    
United States, New York
Clinical Coordinating Center: Stroke Center/The Neurological Institute, Columbia University, 710 West 168th Street     Recruiting
      New York, New York, United States, 10032
      Contact: J. P. Mohr, MS, MD     212-305-8033     jpm10@columbia.edu    
Data Coordinating Center: International Center for Health Outcomes and Innovation Research, Columbia University, 600 West 168th Street     Recruiting
      New York, New York, United States, 10032
      Contact: Alan J. Moskowitz, MD     212-305-9100     ajm4@columbia.edu    
      Contact: Ellen Moquete, RN     212 305 9100     em351@columbia.edu    
1425 Portland Avenue     Recruiting
      Rochester, New York, United States, 14621-3095
      Contact: Joshua Hollander, M.D.     585-922-4371     Joshua.Hollander@viahealth.org    
      Contact: George Edward Vates, M.D.     585-273-3551     Edward_vates@urmc.rochester.edu    
Mount Sinai Hospital, One Gustave L. Levy Place, Department of Neurosurgery- Box 1136     Recruiting
      New York, New York, United States, 10029
      Contact: Jennifer Frontera, MD     212-241-9512     Jennifer.frontera@mountsinai.org    
Long Island College Hospital, 339 Hicks Street     Recruiting
      Brooklyn, New York, United States, 11201
      Contact: Toby Gropen, M.D.     718-780-2897     tgropen@chpnet.org    
SUNY Downstate Medical Center, 451 Clarkson Avenue, Box 1189     Recruiting
      Brooklyn, New York, United States, 11203-2098
      Contact: Sundeep Mangla, M.D.     718-270-2111     smangla@downstate.edu    
New York Presbyterian Hospital, Columbia Campus, Neurological Institute, 710 W. 168th St     Recruiting
      New York, New York, United States, 10032
      Contact: Clinton B. Wright, MD     212-305-1710     cbw7@columbia.edu    
United States, North Carolina
Wake Forest University School of Medicine, Department of Neurology, Medical Center Boulevard     Recruiting
      Winston Salem, North Carolina, United States, 27157-1029
      Contact: John A. Wilson, M.D.     336-716-4020     jawilson@wfubmc.edu    
      Contact: Stephen Glazier, M.D.     336-716-9728     sglazier@wfubmc.edu    
United States, Pennsylvania
University of Pittsburgh Medical Center, Health System Stroke Institute, 200 Lothrop Street- C-400 PUH     Recruiting
      Pittsburgh, Pennsylvania, United States, 15213-2582
      Contact: Lawrence Wechsler, M.D.     412-647-8080     wechslerlr@upmc.edu    
United States, Texas
Seton Medical Center, 1201 West 38th Street     Recruiting
      Austin, Texas, United States, 78701
      Contact: J. Neal Rutledge, M.D.     512-795-5100     nrutledge@austin.rr.com    
Brackenridge Hospital, Brain and Spine Center, 601 East 15th Street     Recruiting
      Austin, Texas, United States, 78701
      Contact: J. Neal Rutledge, M.D.     512-795-5100     nrutledge@austin.rr.com    
Baylor College of Medicine, Department of Neurosurgery, 1709 Dryden Rd. (BCM-650)     Recruiting
      Houston, Texas, United States, 77030-3411
      Contact: Peng Roc Chen, M.D.     713-798-4696     prchen@bcm.tmc.edu    
United States, Virginia
University of Virginia School of Medicine, Department of Neurosurgery, P.O. Box 800212     Recruiting
      Charlottesville, Virginia, United States, 22908
      Contact: Aaron S. Dumont, M.D.     434-924-2735     asd2f@virginia.edu    
United States, Washington
Seattle Neuroscience Institute/Swedish Medical, 550 17th Avenue, Suite 500     Recruiting
      Seattle, Washington, United States, 98122
      Contact: Marc Mayberg, M.D.     206-320-2805     marc.mayberg@swedish.org    
Austria
Rudolfstiftung, Neurochirurgie, Juchgasse 25, A-1030     Recruiting
      Wien, Austria
      Contact: Günther Kleinpeter, MD     43 1 711 65 4301     guenther.kleinpeter@wienkav.at    
Universitätsklinik für Neurologie, Anichstrasse 35, 6020 Innsbruck     Recruiting
      Innsbruck, Austria
      Contact: Erich Schmutzhard, MD     +43 512 5042-3853     erich.schmutzhard@i-med.ac.at    
Canada, Quebec
CHUM Notre Dame Hospital, Department of Radiology, 1560 Sherbrooke Street     Recruiting
      Montreal, Quebec, Canada, H2L 4M1
      Contact: Daniel Roy, M.D.     514-890-8000     Daniel.roy.chum@ssss.gouv.qc.ca    
Finland
Helsinki University Central Hospital, Dept. of Neurosurgery, Topeliuksenkatu 5, Helsinki, P.O. Box 266     Recruiting
      Helsinki, Finland, FI-00029 HUS
      Contact: Aki Laaskso, MD, PhD     +358 9 471 87415     aki.laakso@hus.fi    
      Contact: Juha Hernesniemi, MD, PhD     +358 9 471 87415        
France
European Coordinating Center: Dept. of Neurology, Hôpital Lariboisière, 2 Rue Ambroise Paré, 75475 Paris cedex 10,     Recruiting
      Paris, France
      Contact: Christian Stapf, MD     +33 1 4995 2597     christian.stapf@lrb.aphp.fr    
Hôpital de la Cavale-Blanche, Service de Neurologie, Bd. Tanguy Pringent     Recruiting
      Brest cedex, France, 29609
      Contact: Serge Timsit, MD     +33 2 9834 7300     serge.timsit@chu-brest.fr    
CHU Henri Mondor, Service de Neuroradiologie     Recruiting
      Creteil Cedex, France, 94010
      Contact: André Gaston, MD     +33 1 4981 2641     andre.gaston@hmm.aphp.fr    
Centre Hospitalier Régional et Universitaire de Lille, Clinique de Neurochirurgie, Hopital Roger Salengro, CHRU     Recruiting
      Lille Cedex, France, 59037
      Contact: Jean-Paul Lejeune, MD     +33 3 2044 6615     jp-lejeune@chru-lille.fr    
Hôpital Sainte Anne, Service de Neurochirurgie, Centre Hospitalier Sainte Anne, 1, Rue Cabanis     Recruiting
      Paris, France, 75014
      Contact: François Nataf, MD     +33 1 4565 8232     f.nataf@ch-sainte-anne.fr    
Hôpital Lariboisière, Service de Neuroradiologie, 2, Rue Ambroise Paré     Recruiting
      Paris cedex 10, France, 75475
      Contact: Emmanuel Houdart, MD     +33 1 4995 6135     emmanuel.houdart@lrb.aphp.fr    
Germany
Charité Campus Benjamin Franklin (CCBF), Neurologische Klinik, Hindenburgdamm 30     Recruiting
      Berlin, Germany, 12200
      Contact: Andreas Hartmann, MD     +49 30 84452275     andreas.hartmann@charite.de    
Uniklinikum Dresden, Neuroradiologie, Fetscherstr. 74     Recruiting
      Dresden, Germany, 01307
      Contact: Rüdiger von Kummer, MD     +49 351 458 2660     ruediger.vonkummer@uniklinikum-dresden.de    
Klinikum Großhadern, LMU München, Neurologische Klinik und Poliklinik, Marchionistr. 15     Recruiting
      Munich, Germany, 81377
      Contact: Martin Dichgans, MD     +49 89 7095 3670     martin.dichgans@med.uni-muenchen.de    
Uniklinikum Frankfurt, Institut für Neuroradiologie, Schleusenweg 2-16     Recruiting
      Frankfurt am Main, Germany, 60528
      Contact: Joachim Berkefeld, MD     +49 69 6301 5462     berkefeld@em.uni-frankfurt.de    
Uniklinik Freiburg, Neuroradiology-Neurocenter, Breisacher Str. 64     Recruiting
      Freiburg, Germany, 79106
      Contact: Martin Schumacher, MD     +49 761 270 5180     martin.schumacher@uniklinik-freiburg.de    
Berufsgenossenschaftliche Kliniken Bergmannstrost, Klinik für Neurochirurgie, Merseburger Str. 165     Recruiting
      Halle, Germany, 06112
      Contact: Hans Jörg Meisel, MD     +49 345 132 7404     meisel@bergmannstrost.com    
Universitätsklinik Heidelberg, Department of Neurosurgery, Im Neuenheimer Feld 400     Recruiting
      Heidelberg, Germany, 69120
      Contact: Berk Orakcioglu, MD     +49 6221 56 38922     berk.orakcioglu@med.uni-heidelberg.de    
      Contact: Andreas Unterberg, MD     +49 6221 56 38922        
Neuroradiologie, Zentrum für Nervenheilkunde, Rudolf-Bultmann-Str. 8     Recruiting
      Marburg, Germany, 35039
      Contact: Siegfried Bien, MD     +49 6421 28 66256     biens@mailer.uni-marburg.de    
Universitätsklinikum Essen, Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Hufelandstraße 55     Recruiting
      Essen, Germany, 45147
      Contact: Isabel Wanke, MD     +49 201 723-1509     isabel.wanke@uni-due.de    
      Contact: Michael Forsting, MD     +49 201 723-1509        
Italy
Bellaria Hospital, Department of Neurosurgery     Recruiting
      Bologna, Italy, 40139
      Contact: Eugenio Pozzati, M.D.     +39 051 6225111     eugenio.pozzati@ausl.bo.it    
Servizio di Neuroradiologia, Ospedale San Raffaele, Via Olgettina 60     Recruiting
      Milano, Italy, 20131
      Contact: Giuseppe Scotti, MD     +39 (02) 2643 2239     scotti.giuseppe@hsr.it    
Netherlands
Utrecht University Hospital, Heidelberglaan 100, 3584 CX     Recruiting
      Utrecht, Netherlands
      Contact: H. Bart van der Worp     + 31 30 2509111     h.b.vanderworp@umcutrecht.nl    
Department of Neurosurgery, Universitair Medisch Centrum Groningen Hanzeplein 1     Recruiting
      Groningen, Netherlands, 9700
      Contact: J.M.C. van Dijk, MD     +31 050 361 6161     j.m.c.van.dijk@nchir.umcg.nl    
Spain
Hospital Universitari de Bellvitge, Sección de Neuroradiologia, c/ Feixa Llarga s/n, L'Hospitalet de Llobregat     Recruiting
      Barcelona, Spain, 08907
      Contact: Maria Angels De Miquel, MD     +34 93 260 7536     mademiquel@csub.scs.es    
Switzerland
Inselspital, Neurologische Klinik, 3010 Bern     Recruiting
      Schweiz, Switzerland
      Contact: Marcel Arnold, MD     +41 31 632 3156     marcel.arnold@insel.ch    
United Kingdom
Frenchay Hospital, Neuroradiology Department     Recruiting
      Bristol, United Kingdom, BS 16 1LE
      Contact: Andrew Molyneux, MD     +44 117 975 3982     andrew.molyneux@nbt.nhs.uk    
Department of Neurology, Royal Hallamshire Hospital, Glossop Road     Recruiting
      Sheffield, United Kingdom, 810 2JF
      Contact: Kirsty Harkness, MD     +44 114 271 3810     kirsty.harkness@sth.nhs.uk    
Walton Centre for Neurology, Lower Lane Fazakerley     Recruiting
      Liverpool, United Kingdom, L9 7LJ
      Contact: Mohsen , Javadpour, MD     +44 151 5671     mohsen.javadpour@thewaltoncentre.uhs.uk    
Institute of Neurology, Box 6, The National Hospital, Queen Square     Recruiting
      London, United Kingdom, WC12N 3BG
      Contact: Nicholas Losseff, MD     020 7829 8753     nicholas.losseff@uclh.nhs.uk    
Consultant Neurologist, Department of Neurology, Leeds General Infirmary, Great George Street     Recruiting
      Leeds, United Kingdom, LS1 3EX
      Contact: Ahmad Hassan, MD     +44 113 392 8132     ahmad.hassan@leedsth.nhs.uk    
      Contact: John Bamford, MD     +44 113 392 8132        
Imaging Directorate, Derriford Hospital     Recruiting
      Plymouth, United Kingdom, PL6 8DH
      Contact: William M. Adams, MD     +44 175 251 7917     william.adams@phnt.swest.nhs.uk    
Western General Hospital, Bramwell Dott Building, Department of Clinical Neurosciences, Crewe Road     Recruiting
      Edinburgh, United Kingdom, EH4 2XU
      Contact: Rustam Al-Shahi Salman, MD     +44 131 537 2915     rustam.al-shahi@ed.ac.uk    

Sponsors and Collaborators
Columbia University
National Institute of Neurological Disorders and Stroke (NINDS)

Investigators
Principal Investigator:     J.P. Mohr, MS, MD     Stroke Center/The Neurological Institute, Columbia University    
Principal Investigator:     Alan J. Moskowitz, MD     InCHOIR, Columbia University    
Investigator:     Deborah Ascheim, MD     InCHOIR, Columbia University, Co-PI    
Investigator:     Annetine Gelijns, PhD     InCHOIR, Columbia University, Co-PI    
Investigator:     Michael Parides, PhD     InCHOIR, Columbia University, Co-PI    
Principal Investigator:     Christian Stapf, MD     Clinical Coordinating Center, Europe    
Investigator:     Eric Vicaut, MD     Clinical Coordinating Center, Europe, Co-PI    
Investigator:     Claudia S. Moy, PhD     NINDS, Co-PI    





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