Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
Disorders of the Eye Following Cataract Surgery
|Study Design:||Observational Model: Case-Only
Time Perspective: Cross-Sectional
|Official Title:||Evaluation of Ocular Flora in Patients Undergoing Cataract Surgery. An Observational Study|
- Characterization of the ocular flora [ Time Frame: At least 14 days before surgery ] [ Designated as safety issue: No ]Isolated organisms will be identified and characterized
- Eradication rate [ Time Frame: Day of surgery ] [ Designated as safety issue: No ]In case of positive swab at the screening visit, bacteria eradication will be evaluated before surgery
- Antibiotic susceptibility [ Time Frame: At least 14 days before surgery ] [ Designated as safety issue: No ]Select isolates recovered will be tested for antibiotic susceptibility to netilmicin, tobramycin, chloramphenicol, ofloxacin, levofloxacin, moxifloxacin, azithromycin , meticillin, cefuroxime and vancomycin.
Biospecimen Retention: Samples Without DNA
Conjunctival and palpebral swab of the eye undergoing surgery
|Study Start Date:||April 2014|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||September 2014 (Final data collection date for primary outcome measure)|
Patients undergone cataract surgery
A conjunctival and palpebral swab will executed at least 14 days before routine cataract surgery. Isolates will be identified using standard microbiological protocols. In vitro susceptibility will be determined using a breakpoint minimal inhibitory concentrations. In case of positivity, the swab will be repeated the day of surgery. Topical antibiotic may be used in case of positivity at the discretion of the surgeon. Descriptive statistics will be calculated.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02124603
|Contact: Marcello Santocono, MDfirstname.lastname@example.org|
|Casa di Cura Di Stefano||Recruiting|
|Catania, Italy, 95100|
|Contact: Antonio Gerace email@example.com|
|Principal Investigator: Marcello Santocono, MD|
|Principal Investigator:||Marcello Santocono, MD||Casa Di Cura Di Stefano Catania (Italy)|