Trial record 4 of 179 for:    Open Studies | "Coronary Artery Bypass"

Predicting Acute Kidney Injury After Coronary Artery Bypass Graft

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Samsung Medical Center
Sponsor:
Information provided by (Responsible Party):
WonHo Kim, Samsung Medical Center
ClinicalTrials.gov Identifier:
NCT02081261
First received: March 5, 2014
Last updated: June 19, 2014
Last verified: June 2014
  Purpose

Acute kidney injury after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. There have been many studies reporting risk factor of acute kidney injury after cardiac surgery, but the influence of perioperative variables related to anesthesia and perioperative medication has not been evaluated fully. The investigators attempt to evaluate the influence of preoperative medication, preoperative albumin level, uric acid concentration, anesthesia technique, use of hydroxy ethyl starch, blood glucose level, intraoperative medication, and hemodynamic variables during surgery on the incidence of acute kidney injury after coronary artery bypass graft.


Condition Intervention
Coronary Artery Bypass Surgery
Acute Kidney Injury
Creatinine
Mortality
Procedure: Coronary artery bypass surgery

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Predicting Acute Kidney Injury After Coronary Artery Bypass Graft : a Simplified Clinical Risk Scoring Model

Resource links provided by NLM:


Further study details as provided by Samsung Medical Center:

Primary Outcome Measures:
  • Acute kidney injury diagnosis defined by RIFLE criteria [ Time Frame: during 7 days after surgery ] [ Designated as safety issue: Yes ]
    Acute kidney injury diagnosis defined by RIFLE criteria (for Risk, Injury, Failure, Loss, End-stage kidney disease) during seven days after surgery


Secondary Outcome Measures:
  • Acute kidney injury as defined by AKIN (acute kidney injury network) criteria [ Time Frame: within 48 hours after surgery ] [ Designated as safety issue: Yes ]
    Acute kidney injury as defined by AKIN (acute kidney injury network) criteria


Estimated Enrollment: 1300
Study Start Date: January 2014
Estimated Study Completion Date: August 2014
Estimated Primary Completion Date: August 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Coronary artery bypass surgery
patients who underwent coronary artery bypass surgery between 2010 and 2013 in Samsung Medical Center
Procedure: Coronary artery bypass surgery
coronary artery bypass surgery

Detailed Description:

Acute kidney injury after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. There have been many studies reporting risk factor of acute kidney injury after cardiac surgery, but the influence of perioperative variables related to anesthesia and perioperative medication has not been evaluated fully. The investigators attempt to evaluate the influence of preoperative medication, preoperative albumin level, uric acid concentration, anesthesia technique, use of hydroxy ethyl starch, blood glucose level, intraoperative medication, and hemodynamic variables during surgery on the incidence of acute kidney injury after coronary artery bypass graft.

  Eligibility

Ages Eligible for Study:   20 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

patients who underwent coronary artery bypass surgery during between 2010 and 2013 in Samsung Medical Center

Criteria

Inclusion Criteria:

  • patients who underwent coronary artery bypass surgery during between 2010 and 2013 in Samsung Medical Center

Exclusion Criteria:

  • lack of postoperative creatinine or urine output data
  • patients who expired within 24hours after surgery
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT02081261

Contacts
Contact: Won Ho Kim, MD 82-55-290-6072 wonhokim.ane@gmail.com

Locations
Korea, Republic of
Samsung Medical Center Recruiting
Seoul, Korea, Republic of, 135-710
Contact: Won Ho Kim, MD    82-2-3410-2470    wonhokim.ane@gmail.com   
Sponsors and Collaborators
Samsung Medical Center
  More Information

No publications provided

Responsible Party: WonHo Kim, Assistant Professor, Samsung Medical Center
ClinicalTrials.gov Identifier: NCT02081261     History of Changes
Other Study ID Numbers: 2013-12-116
Study First Received: March 5, 2014
Last Updated: June 19, 2014
Health Authority: South Korea: Institutional Review Board

Keywords provided by Samsung Medical Center:
coronary artery bypass surgery
acute kidney injury
creatinine
mortality

Additional relevant MeSH terms:
Acute Kidney Injury
Wounds and Injuries
Renal Insufficiency
Kidney Diseases
Urologic Diseases

ClinicalTrials.gov processed this record on August 28, 2014