Trial record 2 of 29 for:    Pain | Open Studies | Exclude Unknown | NCCAM

Study of Pain Processing in Experienced Yoga Practitioners

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2013 by National Institutes of Health Clinical Center (CC)
Sponsor:
Collaborators:
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Center for Complementary and Alternative Medicine (NCCAM) )
ClinicalTrials.gov Identifier:
NCT02055235
First received: February 4, 2014
Last updated: September 13, 2014
Last verified: December 2013
  Purpose

Background:

- Different people perceive the same pain differently. Mood, attention, stress, and personality affect how we feel pain. Researchers want to know whether people who do yoga perceive pain differently than people who do not practice yoga, meditation, or martial arts. They also want to study if cortisol, a stress hormone, relates to pain or brain differences.

Objective:

- To study the effects of yoga on the body s stress response, pain perception, and the brain s structure and pain response.

Eligibility:

  • Right-handed adults 30 years and older who practice yoga regularly.
  • Healthy right-handed volunteers 30 years and older who do at least mild exercise but no yoga or martial arts.

Design:

  • Visit 1: Participants will be screened with medical history and physical exam. They will have blood and urine tests and electrocardiogram to measure heart activity.
  • At home, participants will wear a heart monitor for 1 day and collect 5 saliva samples daily for seven days.
  • Visit 2: Participants will undergo tests in a chair or in a mock MRI machine. They will lie on a table that slides into a cylinder.
  • A heating device will be placed on their leg and heated periodically for few seconds at a time.
  • They will give saliva samples.
  • Heart rate, respiration, etc. will be monitored.
  • They will fill out questionnaires.
  • Visit 3: Participants will answer questions and repeat Visit 2 tests. Tests will be done in the real MRI machine. The scanner makes loud knocking sounds. Participants will get earplugs. Participants will be in the scanner about 1 hour with a coil over their head.

Condition
Pain

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Pain Processing and Pain Control in Experienced Yoga Practitioners

Further study details as provided by National Institutes of Health Clinical Center (CC):

Primary Outcome Measures:
  • Pain perception (pain ratings) [ Time Frame: 22 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Brain acivations, brain anatomy, autonomic response, cortisol [ Time Frame: 22 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 120
Study Start Date: January 2014
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   30 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria
  • FOR YOGA PRACTITIONERS:

You may qualify if you are:

  • at least 30 years old
  • an experienced yoga practitioner and practice regularly
  • fluent in English
  • right-handed
  • in good health

You may not qualify if you:

  • have a major medical condition
  • suffer from chronic pain
  • are pregnant or breast-feeding
  • have a fear of enclosed spaces (claustrophobia)

FOR HEALTHY CONTROLS:

You may qualify if you are:

  • at least 30 years old
  • fluent in English
  • right-handed
  • in good health

You may not qualify if you:

  • practice yoga, meditation, or martial arts
  • have a major medical condition
  • suffer from chronic pain
  • are pregnant or breast-feeding

have a fear of enclosed spaces (claustrophobia)

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT02055235

Contacts
Contact: Chantal Villemure, Ph.D. (301) 436-8989 chantal.villemure@nih.gov

Locations
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)    800-411-1222 ext TTY8664111010    prpl@mail.cc.nih.gov   
Sponsors and Collaborators
Investigators
Principal Investigator: Mary C Bushnell, Ph.D. National Center for Complementary and Alternative Medicine (NCCAM)
  More Information

Additional Information:
Publications:
Responsible Party: National Institutes of Health Clinical Center (CC) ( National Center for Complementary and Alternative Medicine (NCCAM) )
ClinicalTrials.gov Identifier: NCT02055235     History of Changes
Other Study ID Numbers: 140054, 14-AT-0054
Study First Received: February 4, 2014
Last Updated: September 13, 2014
Health Authority: United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):
Brain
Pain
Yoga

ClinicalTrials.gov processed this record on September 16, 2014