Review of Kidney Biopsies of Dent Disease Patients
This study is being done to obtain pathology reports from all patients in the Dent disease registry who have had a kidney biopsy. The investigator will collect the biopsy slides and reports in an attempt to determine if they have any common findings.
|Study Design:||Observational Model: Cohort
Time Perspective: Retrospective
|Official Title:||Systematic Review of Clinical Biopsies of Dent Disease Patients|
- Biopsy changes [ Time Frame: 2 years ] [ Designated as safety issue: No ]The primary outcome will be to determine the number of glomeruli, percent globally sclerotic glomeruli, percent focally sclerotic glomeruli, and the severity of interstitial fibrosis (none, mild, moderate, severe) and interstitial crystals (none, mild, moderate, severe)
|Study Start Date:||October 2013|
|Estimated Study Completion Date:||October 2015|
|Estimated Primary Completion Date:||October 2015 (Final data collection date for primary outcome measure)|
Dent Disease patients
Patients with diagnosed Dent Disease
Procedure: Renal Biopsy
Other Name: All patients in the Dent Disease Registry with a previous renal biopsy.
If the patient agrees to be in the study, the patient will be asked to participate in the following:
- Sign a consent form indicating the patient's willingness to participate.
- Provide a signed medical release form allowing the investigator to request your official kidney biopsy reports, and also allowing the investigator to request the original slides for review. At the end of the study, all slides will be returned to the referring facility.
- The investigator will also review your medical record
Please refer to this study by its ClinicalTrials.gov identifier: NCT02022189
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Contact: Alicia M Meek 507-255-4347 firstname.lastname@example.org|
|Contact: Mayo Clinic Rare Kidney Stone Consortium 800-270-4637 email@example.com|
|Principal Investigator: John C. Lieske, M.D.|
|Principal Investigator:||John C Lieske, M.D.||Mayo Clinic|