Attentional Bias and Attentional Bias Modification Treatment in Obsessive-compulsive Disorder

This study is currently recruiting participants.
Verified December 2013 by University of Sao Paulo
Sponsor:
Information provided by (Responsible Party):
Roseli Shavitt, University of Sao Paulo
ClinicalTrials.gov Identifier:
NCT02014194
First received: November 25, 2013
Last updated: December 17, 2013
Last verified: December 2013
  Purpose

Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.


Condition Intervention
Obsessive-compulsive Disorder
Behavioral: attentional bias modification treatment

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Attentional Bias and Attentional Bias Modification Treatment in Obsessive-compulsive Disorder

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • Percentage of reduction of attentional bias [ Time Frame: Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10. ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Reduction of anxiety symptoms [ Time Frame: Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks) ] [ Designated as safety issue: No ]

Estimated Enrollment: 30
Study Start Date: November 2013
Estimated Primary Completion Date: July 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: attentional bias modification, 2 arms
Measure of attentional bias modification treatment after 10 sessions of attentional bias modification (two arms). There are two arms with 15 OCD patients each one.
Behavioral: attentional bias modification treatment
The attentional bias modification treatment is a behavioral computerized program (software e-prime)

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria: - 30 patients with obsessive-compulsive diagnosis according to DSM-V

  • 30 health controls

Exclusion Criteria: - doing any kind of behavioral therapy in the moment

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT02014194

Locations
Brazil
University of Sao Paulo Medical School Recruiting
Sao Paulo, Brazil, 05403010
Contact: Maria Alice Mathis, Phd    55 11 26616972    alicedemathis@gmail.com   
Sponsors and Collaborators
Roseli Shavitt
  More Information

No publications provided

Responsible Party: Roseli Shavitt, MD, Phd, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT02014194     History of Changes
Other Study ID Numbers: 13674113.2.0000.0068
Study First Received: November 25, 2013
Last Updated: December 17, 2013
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by University of Sao Paulo:
Attentional Bias
Attentional Bias modification treatment

Additional relevant MeSH terms:
Obsessive-Compulsive Disorder
Compulsive Personality Disorder
Anxiety Disorders
Mental Disorders
Personality Disorders

ClinicalTrials.gov processed this record on April 17, 2014