Can Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation Improve Survival of out-of Hospital Cardiac Arrest?

This study is not yet open for participant recruitment. (see Contacts and Locations)
Verified December 2013 by Seoul National University Hospital
Sponsor:
Collaborators:
Korean Center for Disease Control and Prevention
Seoul Metropolitan Government Health and Welfare Office
Seoul Metropolitan Fire and Disaster Headquater
Korea Association for Safety Community
Information provided by (Responsible Party):
Sang Do Shin, Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT02010151
First received: December 9, 2013
Last updated: NA
Last verified: December 2013
History: No changes posted
  Purpose

The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).


Condition Intervention
Out of Hospital Cardiac Arrest
Other: NAD-CPR

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Population Based Intervention Trial of Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation

Resource links provided by NLM:


Further study details as provided by Seoul National University Hospital:

Primary Outcome Measures:
  • Survival to discharge [ Time Frame: 40 months ] [ Designated as safety issue: No ]
    difference of survival to discharge rate of before intervention period (20 months) and intervention period (20 months)


Secondary Outcome Measures:
  • Pre-hospital return of spontaneous circulation (ROSC) [ Time Frame: 40 months ] [ Designated as safety issue: No ]
    difference of pre-hospital ROSC rate of before intervention period (20 months)and intervention period (20 months)

  • survival to admission [ Time Frame: 40 months ] [ Designated as safety issue: No ]
    difference of survival to admission rate of before intervention period (20 months)and intervention period (20 months)

  • good neurological recovery [ Time Frame: 40 months ] [ Designated as safety issue: No ]
    Cerebral performance category 1 or 2 is defined as good neurological recovery. Secondary outcome is difference of good neurological recovery rate of before intervention period (20 months)and intervention period (20 months).


Estimated Enrollment: 3776
Study Start Date: December 2013
Estimated Study Completion Date: October 2015
Estimated Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: NAD-CPR
When dispatcher detects a patient with OHCA, the dispatcher activates trained neighborhoods by informing events nearby using short message service via cellular phone. The neighborhood within geographically accessible area who could perform effective CPR and defibrillation would be alerted with event of OHCA and the nearest AED.
Other: NAD-CPR
When Dispatcher detects OHCA, short message service (SMS)about the OHCA event and information about the location of nearest AED is sent to trained laypersons within geographically accessible area.
No Intervention: Conventional dispatcher assisted CPR
When dispatcher detects OHCA, they instruct the caller with CPR instructions. This is conventional dispatcher assisted CPR performed in Seoul.

Detailed Description:

Out-of-hospital cardiac arrest (OHCA) is a major health problem, occurring in about 1 in 1,500 adults in the developed countries each year. Although layperson CPR and defibrillation are crucial components of chain of survival, layperson CPR rate and it's quality is low and public-access defibrillation (PAD) program is not cost-effective.If trained bystanders can know the information of occurrence of OHCA and nearest place for automated external defibrillator (AED) at the same time by dispatch center, these neighborhoods could run and give high quality CPR and early defibrillation. If this protocol ,Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation(NAD-CPR), is introduced to community, it may improve survival of OHCA.

  Eligibility

Ages Eligible for Study:   15 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • all OHCA with presumed cardiac etiology more than 15 years old
  • assessed by emergency medical service (EMS) providers dispatched by dispatch center
  • dispatcher detected OHCA patients

Exclusion Criteria:

  • OHCA with non-cardiac etiology
  • prolonged cardiac arrest with a suspected duration more than 30 minutes
  • cases with rigor mortis or rivor mortis, decapitated or decomposed body
  • Non detected cases by dispatcher
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT02010151

Contacts
Contact: Joo Yeong Kim, MD 82-2-2072-1700 blj01he@gmail.cm

Locations
Korea, Republic of
Seoul Metropolitan City Not yet recruiting
Seoul, Korea, Republic of
Sub-Investigator: Kyoung Jun Song, MD         
Sub-Investigator: Eui Jung Lee, MD         
Sub-Investigator: Joo Yeong Kim, MD         
Sub-Investigator: Yu Jin Lee, MD         
Sub-Investigator: Ju Ok Park, MD         
Sub-Investigator: Ki Jeong Hong, MD         
Sub-Investigator: So Young Ha, MD         
Sub-Investigator: Kwang Soo Bae, MD         
Sub-Investigator: Jeong Eun Kim, MPH         
Sponsors and Collaborators
Seoul National University Hospital
Korean Center for Disease Control and Prevention
Seoul Metropolitan Government Health and Welfare Office
Seoul Metropolitan Fire and Disaster Headquater
Korea Association for Safety Community
Investigators
Principal Investigator: Sang Do Shin, MD, PhD Seoul National University Hospital
  More Information

No publications provided

Responsible Party: Sang Do Shin, Associated Professor, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT02010151     History of Changes
Other Study ID Numbers: SNUEMS201309
Study First Received: December 9, 2013
Last Updated: December 9, 2013
Health Authority: South Korea: Institutional Review Board

Keywords provided by Seoul National University Hospital:
Out of Hospital Cardiac Arrest
Cardiopulmonary Resuscitation
dispatch
emergency medicine

Additional relevant MeSH terms:
Heart Arrest
Out-of-Hospital Cardiac Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on August 20, 2014