Optical Coherence Tomography (OCT) in Retinal Vasculitis
Retinal vasculitis is a sight-threatening inflammation that involves the blood vessels of the retina, the tissue that lines the inside of the eye. This inflammation may occur on its own or as a result of an infectious, cancerous, or inflammatory disorder.
Optical coherence tomography (OCT) is an imaging technology that can perform non-contact cross-sectional imaging of retinal and choroidal tissue structure in real time. It is similar to ultrasound imaging, except that OCT measures the intensity of reflected light rather than sound waves.
The purpose of this study is to see if non-invasive OCT technology can diagnose retinal vasculitis as well as the more invasive fluorescein angiography, which requires an injection of dye into the vein of an arm of a patient. The study will also compare the mapping of blood vessels (angiography) and loss of blood flow (ischemia) by fluorescein angiography and OCT.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Evaluation of the Utility of OCT Angiography in Assessing Vascular Perfusion in Retinal Vasculitis|
- Blood flow patterns in retinal vasculitis [ Time Frame: 24 months ] [ Designated as safety issue: No ]To determine if identifying early changes in blood vessel patterns will aid in early diagnosis and treatment of retinal vasculitis.
- Ischemia in retinal vasculitis [ Time Frame: 24 months ] [ Designated as safety issue: No ]To determine if identifying lost or reduced blood flow will aid in early diagnosis and treatment of retinal vasculitis
|Study Start Date:||January 2014|
|Estimated Primary Completion Date:||January 2016 (Final data collection date for primary outcome measure)|
Retinal Vasculitis Group
Up to 35 patients diagnosed with retinal vasculitis will be considered and evaluated for enrollment in this study.
|Contact: Denny Romfhemail@example.com|
|Contact: Janice Ladwigfirstname.lastname@example.org|
|United States, Oregon|
|Portland, Oregon, United States, 97239|
|Contact: Denny Romfh 503-494-4351 email@example.com|
|Contact: Janice Ladwig 503-494-8024 firstname.lastname@example.org|
|Sub-Investigator: Neal Palejwala, MD|
|Sub-Investigator: Justin Baynham, MD|
|Sub-Investigator: John Campbell, MD, MPH|
|Sub-Investigator: Andreas Lauer, MD|
|Sub-Investigator: Christina Flaxel, MD|
|Sub-Investigator: Thomas Hwang, MD|
|Sub-Investigator: Michael Klein, MD|
|Sub-Investigator: Steven Bailey, MD|
|Sub-Investigator: David Huang, MD, PhD|
|Principal Investigator:||Phoebe Lin, MD, PhD||Oregon Health and Science University|