Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue

This study is currently recruiting participants.
Verified September 2013 by University of Aarhus
Sponsor:
Information provided by (Responsible Party):
Esben Søndergaard, University of Aarhus
ClinicalTrials.gov Identifier:
NCT01949714
First received: September 20, 2013
Last updated: NA
Last verified: September 2013
History: No changes posted
  Purpose
  • To investigate the effect of catecholamine excess on brown fat.
  • To evaluate the effect of brown fat on energy expenditure and lipid and glucose metabolism

Condition Intervention
Pheochromocytoma
Incidentaloma
Procedure: Removal of adrenal tumor

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue

Resource links provided by NLM:


Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • [18F]FDG uptake in brown adipose tissue [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 15
Study Start Date: August 2013
Estimated Primary Completion Date: January 2017 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Pheochromocytoma patients
Pheochromocytoma patients
Procedure: Removal of adrenal tumor
Incidentaloma patients
Incidentaloma patients
Procedure: Removal of adrenal tumor

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with adrenal tumors

Criteria

Inclusion Criteria:

  • 10 patients with pheochromocytoma
  • 5 patients with incidentaloma without hormone production
  • Age > 18 years

Exclusion Criteria:

- None

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01949714

Contacts
Contact: Esben Søndergaard, MD, PhD 4578461631 esbens@dadlnet.dk

Locations
Denmark
Department of Endocrinology MEA, Aarhus Hospital Recruiting
Aarhus C, Please Select, Denmark, 8000
Contact    4578461631      
Principal Investigator: Esben Søndergaard, MD, PhD         
Sponsors and Collaborators
University of Aarhus
  More Information

No publications provided

Responsible Party: Esben Søndergaard, MD, PhD, Post Doc, University of Aarhus
ClinicalTrials.gov Identifier: NCT01949714     History of Changes
Other Study ID Numbers: ES-0005
Study First Received: September 20, 2013
Last Updated: September 20, 2013
Health Authority: Denmark: Danish Dataprotection Agency

Additional relevant MeSH terms:
Pheochromocytoma
Paraganglioma
Neuroendocrine Tumors
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Nerve Tissue

ClinicalTrials.gov processed this record on April 15, 2014