International Multicentre Prevalence Study on Sepsis (IMPRESS)

This study has been completed.
Sponsor:
Collaborator:
Society of Critical Care Medicine (SCCM)
Information provided by (Responsible Party):
European Society of Intensive Care Medicine
ClinicalTrials.gov Identifier:
NCT01943747
First received: September 12, 2013
Last updated: August 19, 2014
Last verified: August 2014
  Purpose

To mark 10 years of the Surviving Sepsis Campaign (SSC), and timed to coincide with World Sepsis Day, on September 13, 2013, the SSC, ESICM and SCCM will be conducting an international point prevalence study of severe sepsis and septic shock. The goal of this project is to determine the world wide burden of severe sepsis and define current practices of sepsis care internationally. The study is a simple data collection exercise for patients presenting with either severe sepsis or septic shock on World Sepsis Day.


Condition
Severe Sepsis
Septic Shock

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Surviving Sepsis Campaign. International Multicentre Prevalence Study on Sepsis.

Resource links provided by NLM:


Further study details as provided by European Society of Intensive Care Medicine:

Primary Outcome Measures:
  • 28-Day Mortality [ Time Frame: one week ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Organ Failure [ Time Frame: one week ] [ Designated as safety issue: No ]

Other Outcome Measures:
  • Length of Stay in the Hospital [ Time Frame: one week ] [ Designated as safety issue: No ]

Estimated Enrollment: 1000
Study Start Date: November 2013
Study Completion Date: January 2014
Primary Completion Date: November 2013 (Final data collection date for primary outcome measure)
Detailed Description:

De--‐identified patient--‐level data will be collected on patients presenting to a participating intensive care unit or emergency department with severe sepsis or septic shock over a 24 hour period from 00:00 to 24:00 November 07, 2013. De--‐identified data that is already collected as part of routine clinical care will be collected for this study. Data to be collected includes hospital and ICU characteristics, patient characteristics, severity of illness, and adherence to SSC bundle elements and mortality. It will take between 30--‐60 minutes to collect and enter data for each patient admitted with severe sepsis or septic shock over the 24 hours study period.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

patients presenting with either severe sepsis or septic shock

Criteria

Inclusion Criteria:

To be eligible patients must have all of the following:

  • Must be admitted or transferred to either the ED or an Intensive Care Unit.
  • Have a high clinical suspicion of an infection
  • Have sepsis as defined by an infection together with two or more SIRS criteria
  • Evidence of acute organ dysfunction and/or Shock.

Exclusion Criteria:

  • Patients less than 18 years of age
  • Patients in whom the sepsis has been present from before the beginning of the study period
  • Any patients previously included in the study during the same study period
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01943747

Locations
Belgium
All centres willing to contribute are welcome.
Brussels, Belgium
Sponsors and Collaborators
European Society of Intensive Care Medicine
Society of Critical Care Medicine (SCCM)
Investigators
Principal Investigator: Andrew RHODES, MD, PhD European Society of Intensive Care Medicine
  More Information

Additional Information:
No publications provided

Responsible Party: European Society of Intensive Care Medicine
ClinicalTrials.gov Identifier: NCT01943747     History of Changes
Other Study ID Numbers: IMPRESS
Study First Received: September 12, 2013
Last Updated: August 19, 2014
Health Authority: Belgium: European Society of Intensive Care Medicine

Keywords provided by European Society of Intensive Care Medicine:
sepsis
severe sepsis
septic shock
infection
organ dysfunction
quality improvement

Additional relevant MeSH terms:
Sepsis
Shock, Septic
Toxemia
Infection
Inflammation
Pathologic Processes
Shock
Systemic Inflammatory Response Syndrome

ClinicalTrials.gov processed this record on October 20, 2014