Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Microcirculatory Assessment in Patients With Trauma and Severe Burns|
- dysfunctional capillary density correlates with development of multiple organ failure [ Time Frame: approximately 1 year to assess outcome measure ] [ Designated as safety issue: No ]
|Study Start Date:||April 2012|
|Estimated Study Completion Date:||June 2015|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints.
Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 & Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,& closing of surgical wound.
Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock).
The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)
|Contact: William O Richards, MDfirstname.lastname@example.org|
|United States, Alabama|
|University of South Alabama Medical Center||Recruiting|
|Mobile, Alabama, United States, 36617|
|Contact: William O. Richards, MD 251-471-7993 email@example.com|
|Principal Investigator: William O. Richards, MD|
|Sub-Investigator: Diego Alvarez, PhD|
|Study Chair:||William O Richards, MD||University of South Alabama, Department of Surgery|