Obesity and Mortality

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
David Allison, Phd, University of Alabama at Birmingham
ClinicalTrials.gov Identifier:
NCT01889225
First received: June 20, 2013
Last updated: July 31, 2013
Last verified: July 2013
  Purpose

Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.


Condition
Obesity and Overweight

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:


Further study details as provided by University of Alabama at Birmingham:

Primary Outcome Measures:
  • Change in Years of Life Lost Associated with Standard BMI categories Over Calendar Time [ Time Frame: Between 1960 and 2000 (up to 40 years) ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Change in Adjusted Hazard Ratio Over Calendar Time for Standard BMI Categories [ Time Frame: Between 1960 and 2000 (up to 40 years) ] [ Designated as safety issue: No ]

Estimated Enrollment: 311982
Study Start Date: January 2008
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
Multiple Risk Factor Intervention Trial - Usual Group
Multiple Risk Factor Intervention Trial - Referred Group
Framingham Heart study
Framingham Offspring cohort
Atherosclerosis Risk In Communities
Charleston Heart study
Cardiovascular Health study
Rancho Bernardo study
Nurses' Health I study
Panel Study Income Dynamics
MRFIT Referred Care
HDFP Referral Care
Alameda County Health and Ways of Living Study
Nurses' Health II study
Tecumseh County Health study
EPESE-East Boston
Established Populations for Epidemiologic Studies of the Elderly-East Boston
EPESE-Duke
Established Populations for Epidemiologic Studies of the Elderly-Duke
EPESE-Iowa
Established Populations for Epidemiologic Studies of the Elderly-Iowa
EPESE-New Haven
Established Populations for Epidemiologic Studies of the Elderly-New Haven

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

U.S. based prospective cohorts of adults

Criteria

Inclusion Criteria:

  • U.S. based studies with at least 1500 subjects
  • At least 5 years of mortality follow-up
  • BMI measured or self-reported available at 2 or more separate calendar time
  • Subjects varied in age at baseline

Exclusion Criteria:

  • Any study that does not meet the inclusion criteria was excluded
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01889225

Sponsors and Collaborators
University of Alabama at Birmingham
Investigators
Principal Investigator: David B Allison, Ph.D. University of Alabama at Birmingham
  More Information

No publications provided

Responsible Party: David Allison, Phd, Principal Investigator, University of Alabama at Birmingham
ClinicalTrials.gov Identifier: NCT01889225     History of Changes
Other Study ID Numbers: R01-DK076771-Aim1A, R01DK076771
Study First Received: June 20, 2013
Last Updated: July 31, 2013
Health Authority: United States: National Institute of Health
United States: UAB Institutional Review Board

Additional relevant MeSH terms:
Obesity
Overweight
Overnutrition
Nutrition Disorders
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on August 21, 2014