Retraining Attention to Treat Alcohol Dependence and Social Anxiety (AMP)

This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2013 by University of Cincinnati
Sponsor:
Collaborators:
Miami University
Brown University
Information provided by (Responsible Party):
University of Cincinnati
ClinicalTrials.gov Identifier:
NCT01886716
First received: June 17, 2013
Last updated: August 7, 2013
Last verified: August 2013
  Purpose

The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence. The intervention seeks to reduce symptoms by shifting attention away from alcohol-relevant and/or socially threatening cues. The investigators expect that participants receiving alcohol or anxiety training will experience reductions in those specific symptoms compared to participants in a control condition. The investigators also expect that participants receiving combined alcohol and anxiety training will show the largest reductions in alcohol and anxiety symptoms, relative to participants in any other condition.


Condition Intervention
Alcohol Drinking
Anxiety Disorders
Behavioral: Anxiety Attention Training
Behavioral: Alcohol Attention Training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Cognitive Bias Modification: A Novel Intervention for Alcohol Dependence and Social Anxiety

Resource links provided by NLM:


Further study details as provided by University of Cincinnati:

Primary Outcome Measures:
  • Liebowitz Social Anxiety Scale [ Time Frame: End of Training (4 weeks) ] [ Designated as safety issue: No ]
  • 30-Day Timeline Follow-back for Alcohol and Drugs [ Time Frame: End of Training (4 weeks) ] [ Designated as safety issue: No ]

Estimated Enrollment: 68
Study Start Date: July 2013
Estimated Study Completion Date: December 2014
Estimated Primary Completion Date: November 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Anxiety Attention Training only
Participants will receive Anxiety Attention Training and placebo Alcohol training.
Behavioral: Anxiety Attention Training
Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
Experimental: Alcohol Attention Training only
Participants will receive Alcohol Attention Training and placebo Anxiety training.
Behavioral: Alcohol Attention Training
Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
Experimental: Anxiety + Alcohol Attention Training
Participants will receive both Anxiety Attention Training and Alcohol Attention Training.
Behavioral: Anxiety Attention Training
Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
Behavioral: Alcohol Attention Training
Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
Placebo Comparator: Control Training
Participants will receive placebo Anxiety Training and placebo Alcohol training.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Current alcohol dependence
  • Elevated social anxiety symptoms
  • Willingness to consider cutting down on drinking

Exclusion Criteria:

  • Current psychosis
  • Unmanaged manic symptoms
  • Significant cognitive impairment
  • Other drug use in past month
  • Receiving cognitive behavioral therapy for alcohol use disorder or social anxiety
  • Unable to read
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01886716

Contacts
Contact: Joshua C Magee, Ph.D. joshua.c.magee@gmail.com
Contact: Elise M Clerkin, Ph.D. eliseclerkin@gmail.com

Locations
United States, Ohio
University of Cincinnati Department of Family and Community Medicine Recruiting
Cincinnati, Ohio, United States, 45206
Contact: Joshua C Magee, Ph.D.    614-483-1005    joshuacmagee@gmail.com   
Principal Investigator: Joshua C Magee, Ph.D.         
Sponsors and Collaborators
University of Cincinnati
Miami University
Brown University
Investigators
Principal Investigator: Joshua C Magee, Ph.D. University of Cincinnati
  More Information

No publications provided

Responsible Party: University of Cincinnati
ClinicalTrials.gov Identifier: NCT01886716     History of Changes
Other Study ID Numbers: 1R21AA021151, 1R21AA021151
Study First Received: June 17, 2013
Last Updated: August 7, 2013
Health Authority: United States: Institutional Review Board
United States: Federal Government

Keywords provided by University of Cincinnati:
Alcohol Abuse
Alcohol Dependence
Alcohol Drinking
Social Anxiety
Social Phobia
Anxiety Disorders

Additional relevant MeSH terms:
Anxiety Disorders
Alcohol Drinking
Alcoholism
Drinking Behavior
Alcohol-Related Disorders
Substance-Related Disorders
Mental Disorders
Ethanol
Anti-Infective Agents, Local
Anti-Infective Agents
Therapeutic Uses
Pharmacologic Actions
Central Nervous System Depressants
Physiological Effects of Drugs
Central Nervous System Agents

ClinicalTrials.gov processed this record on July 29, 2014