Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

This study is currently recruiting participants. (see Contacts and Locations)
Verified November 2013 by Charite University, Berlin, Germany
Sponsor:
Information provided by (Responsible Party):
Thi Thai Hien Pham, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier:
NCT01884194
First received: May 24, 2013
Last updated: November 11, 2013
Last verified: November 2013
  Purpose

MRI is useful for diagnosing pinealoblastoma in retinoblastoma patients


Condition
Retinoblastoma
Pineoblastoma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

Resource links provided by NLM:


Further study details as provided by Charite University, Berlin, Germany:

Primary Outcome Measures:
  • Malignancy criteria of pineal gland [ Time Frame: clinical follow-up 1-year after baseline imaging ] [ Designated as safety issue: No ]
    size of pineal gland solid or cystic component (all at baseline)


Estimated Enrollment: 100
Study Start Date: November 2013
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: May 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
Retinoblastoma patients
patients with diagnosed retinoblastoma
non-retinoblastoma patients
aged matched control cohort without the diagnosis of ocular or brain tumor

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

pediatric patients with retinoblastoma

Criteria

Inclusion Criteria:

  • diagnosis of retinoblastoma
  • brain MRI available

Exclusion Criteria:

  • insufficient quality of brain MRI
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01884194

Contacts
Contact: Patrick Asbach, MD +4930450527723 patrick.asbach@charite.de

Locations
Germany
Charite Hospital Berlin Recruiting
Berlin, Germany, 12200
Contact: Patrick Asbach, MD    +4930450527723    patrick.asbach@charite.de   
Sponsors and Collaborators
Charite University, Berlin, Germany
  More Information

No publications provided

Responsible Party: Thi Thai Hien Pham, doctoral candidate, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier: NCT01884194     History of Changes
Other Study ID Numbers: RTB_0305_outcome
Study First Received: May 24, 2013
Last Updated: November 11, 2013
Health Authority: Germany: Ethics Commission

Keywords provided by Charite University, Berlin, Germany:
retinoblastoma
pineoblastoma

Additional relevant MeSH terms:
Retinoblastoma
Pinealoma
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Retinal Neoplasms
Eye Neoplasms
Neoplasms by Site
Eye Diseases
Retinal Diseases
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on August 28, 2014