A Pilot Study Simulating Multifocal Intraocular Lenses in Healthy Subjects
Age related cataracts are responsible for about 51 percent of blindness worldwide and according to the WHO affect about 20 million people, according to the WH . As cataract surgery is firstline treatment in the western world, there is a constant attempt to improve artificial intraocular lenes (IOL).
As for this study, the investigators seek to compare four different IOL designs in in a psychophysiological setting, allowing to assess the impact of these IOLs on vision and psychological processing of visual information.
As these IOLs also have downsides, such as reduced light intensity or image alterations, the subjective preference and overall impression shall be investigated. The healthy subjects look through a stable spectacle frame mounted onto a table, which enables the investigator to insert the different IOLs. This would allow subjective testing of IOLs before surgery.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
- Eearly Treatment Diabetic Retinopathy Study (ETDRS) visual acuity score [ Time Frame: 1 study day ] [ Designated as safety issue: No ]To investigate the psychophysiological impact of different optical setups on visual acuity at far, intermediate and near distance.
|Study Start Date:||April 2013|
|Study Completion Date:||July 2013|
|Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
30 healthy male and female subjects
30 healthy male and female subjects aged 18-35
Cyclopentolatehydrochloride 0.5% (Thilo, Alcon, Vienna), dose: 1 drop for study eye
Please refer to this study by its ClinicalTrials.gov identifier: NCT01873781
|Department of Clinical Pharmacology, Medical University of Vienna|
|Vienna, Austria, 1080|