Physiological Effects of Deferred Cord Clamping (DoppCord)
This is an observational study to see if at birth, flow of blood from a placenta to the baby can be estimated non-invasively using Doppler ultrasound and/or cutaneous perfusion measured using a novel PPG sensor.
Deferred Umbilical Cord Clamping
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Delivery Room and Postnatal Assessment of the Physiological Effects of Deferred Cord Clamping on the Newborn: A Feasibility Study|
- Quantification of blood flow in the umbilical cord or skin [ Time Frame: For Doppler the umbilical cord will be scanned until it is clamped (up to 3 minutes). Blood flow to the skin will be measured for up to 20 minutes as long as this is not interfering with normal clinical care. ] [ Designated as safety issue: No ]The use of either Doppler ultrasound or a photoplethysmographic (PPG) sensor at delivery to measure either blood flow in the umbilical cord or the skin.
- To assess the cardiovascular status of infants undergoing deferred cord clamping in comparison to immediate clamping. [ Time Frame: In the first 3 days after birth. ] [ Designated as safety issue: No ]A number of markers of cardiovascular status will be measured including central and peripheral capillary refill time using a PPG sensor and by the investigators observation, non-invasive blood pressure, heart rate, haemoglobin and haematocrit.
Biospecimen Retention: Samples Without DNA
Umbilical Cord and Blood
|Study Start Date:||May 2013|
|Estimated Study Completion Date:||May 2016|
|Estimated Primary Completion Date:||May 2016 (Final data collection date for primary outcome measure)|
Infants undergoing a deferring of umbilical cord clamping for 30 seconds or more
Immeadiate Cord Clamping
Infants undergoing immediate umbilical cord clamping in the first 20 seconds of life.
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|Contact: Don Sharkey, BMBS PhDfirstname.lastname@example.org|
|University Hospitals Nottingham NHS Trust||Recruiting|
|Nottingham, Nottinghamshire, United Kingdom, NG7 2UH|
|Principal Investigator: Don Sharkey, MBBS PhD|
|Principal Investigator:||Don Sharkey, BMBS PhD||Univeristy of Nottingham|