Physiological Effects of Deferred Cord Clamping (DoppCord)
This is an observational study to see if at birth, flow of blood from a placenta to the baby can be estimated non-invasively using Doppler ultrasound and/or cutaneous perfusion measured using a novel PPG sensor.
Deferred Umbilical Cord Clamping
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Delivery Room and Postnatal Assessment of the Physiological Effects of Deferred Cord Clamping on the Newborn: A Feasibility Study|
- Quantification of blood flow in the umbilical cord or skin [ Time Frame: For Doppler the umbilical cord will be scanned until it is clamped (up to 3 minutes). Blood flow to the skin will be measured for up to 20 minutes as long as this is not interfering with normal clinical care. ] [ Designated as safety issue: No ]The use of either Doppler ultrasound or a photoplethysmographic (PPG) sensor at delivery to measure either blood flow in the umbilical cord or the skin.
- To assess the cardiovascular status of infants undergoing deferred cord clamping in comparison to immediate clamping. [ Time Frame: In the first 3 days after birth. ] [ Designated as safety issue: No ]A number of markers of cardiovascular status will be measured including central and peripheral capillary refill time using a PPG sensor and by the investigators observation, non-invasive blood pressure, heart rate, haemoglobin and haematocrit.
Biospecimen Retention: Samples Without DNA
Umbilical Cord and Blood
|Study Start Date:||May 2013|
|Estimated Study Completion Date:||May 2016|
|Estimated Primary Completion Date:||May 2016 (Final data collection date for primary outcome measure)|
Infants undergoing a deferring of umbilical cord clamping for 30 seconds or more
Immeadiate Cord Clamping
Infants undergoing immediate umbilical cord clamping in the first 20 seconds of life.
Show Detailed Description
Please refer to this study by its ClinicalTrials.gov identifier: NCT01864421
|Contact: Don Sharkey, BMBS PhDfirstname.lastname@example.org|
|University Hospitals Nottingham NHS Trust||Recruiting|
|Nottingham, Nottinghamshire, United Kingdom, NG7 2UH|
|Principal Investigator: Don Sharkey, MBBS PhD|
|Principal Investigator:||Don Sharkey, BMBS PhD||Univeristy of Nottingham|