Assessment of Coronary Artery Disease in Stroke Patients (ACADIS)
This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.
Coronary Artery Disease
|Study Type:||Observational [Patient Registry]|
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Target Follow-Up Duration:||5 Years|
|Official Title:||Prevalence and Characteristics of Coronary Atherosclerosis in Stroke Patients Using Coronary CT Angiography|
- MACE (Major Adverse Cardiac Event) [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]MACE was included as follows: 1) all-cause mortality, 2) myocardial infarction, 3) unstable angina requiring hospitalization
- Revascularization [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]However, early revascularization less than 90days after CCTA scan is excluded from events, because these subjects directly affected by CT findings
- Repeated stroke [ Time Frame: Participants will be followed until Dec. 2013, an expeded average of 5 years ] [ Designated as safety issue: No ]newly developed stroke after CCTA scan
|Study Start Date:||January 2006|
|Estimated Study Completion Date:||December 2015|
|Estimated Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
Coronary artery disease, Stroke
Coronary artery disease, stroke, coronary CT angiography
Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.
Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.
Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01850693
|Contact: Eun Ju Chun, MDfirstname.lastname@example.org|
|Contact: Eun Hee Kim, MDemail@example.com|
|Korea, Republic of|
|Seoul National University Bundang Hospital||Recruiting|
|Seongnam-si, Gyeonggi-do, Korea, Republic of, 436-707|
|Contact: Eun Ju Chun, MD +82-31-787-7618 firstname.lastname@example.org|
|Contact: Eun Hee Kim, MD +82-31-787-7609 email@example.com|
|Principal Investigator: Eun Ju Chun, MD|
|Principal Investigator:||Eun Ju Chun, MD||Department of Radiology, Seoul National University Bundang Hospital|