Positive Psychology for Mood Disorders (PPBPAD)

This study is enrolling participants by invitation only.
Sponsor:
Information provided by (Responsible Party):
Jeff C. Huffman, MD, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT01820286
First received: March 25, 2013
Last updated: August 7, 2014
Last verified: August 2014
  Purpose

The investigators are doing this study to see if "positive psychology" can help adults with depression or bipolar disorder.

Positive psychology involves exercises—short tasks—that try to increase good feelings and emotions, like optimism, happiness, personal strengths, and well-being. Positive psychology exercises might include imagining a bright future, being grateful for good events, forgiving others, and doing kind acts for others.

The investigators want to see if practicing positive psychology exercises after leaving the hospital can increase feelings of hope, optimism, and positive thinking. The investigators are asking you to take part in this research study because you are in the hospital for depression or bipolar disorder.

This research study will compare "positive psychology exercises" to "control condition exercises." During the study, you may take part in control condition exercises instead of positive psychology exercises.


Condition Intervention
Bipolar Disorder
Depression
Behavioral: Positive psychology intervention
Behavioral: Recollection intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Trial of a Positive Psychology Intervention to Reduce Suicide Risk in Patients With Mood Disorders

Resource links provided by NLM:


Further study details as provided by Massachusetts General Hospital:

Primary Outcome Measures:
  • Feasibility of positive psychology exercises [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]

    Feasibility will be measured by:

    1. Completion rate of exercises
    2. Ease of exercises (rated on a 5-point scale)
    3. Helpfulness of exercises (rated on a 5-point scale)


Secondary Outcome Measures:
  • Impact of positive psychology exercises on positive affect [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]

    Positive affect will be measured by:

    1. Optimism score on the Life Orientation Test-Revised (scores range from 3 to 30, with higher scores indicating higher levels of optimism)
    2. Gratitude score on the Gratitude Questionnaire-6 (scores range from 6 to 42, with higher scores indicating higher levels of gratitude)
    3. Positive emotion score on the Positive and Negative Affect Scale (scores range from 10 to 50, with higher scores indicating higher levels of positive emotion)

  • Impact of positive psychology exercises on negative affect [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]

    Negative affect will be measured by:

    1. Hopelessness scores on the Beck Hopelessness Scale (scores range from 0 to 20, with higher scores indicating higher levels of hopelessness).
    2. Suicidal ideation scores on the Concise Health Risk Tracking scale (scores range from 12 to 60, with higher scores indicating higher levels of suicidal ideation)
    3. Depression scores on the Quick Inventory of Depressive Symptomatology-Self Report (scores range from 0 to 27, with higher scores indicating higher levels of depression)


Estimated Enrollment: 30
Study Start Date: March 2013
Estimated Study Completion Date: January 2015
Estimated Primary Completion Date: November 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Positive psychology intervention
4-week positive psychology intervention of 1 positive psychology exercise per week. Exercises will include 1) recalling 3 good events, 2) writing a letter of thankfulness, 3) using a personal strength, 4) envisioning a best possible future.
Behavioral: Positive psychology intervention
Active Comparator: Recollection intervention
4-week recollection intervention of 1 recollection exercise per week. Exercises will include recalling events related to 1) daily activities, 2) health, 3) social life, 4) morning and evening.
Behavioral: Recollection intervention

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patient admitted to Massachusetts General Hospital Inpatient Psychiatric Unit
  • Age 18 and older
  • Able to read and write in English
  • Admission diagnosis of major depressive disorder or bipolar affective disorder (current depressive episode), confirmed using the Mini International Neuropsychiatric Interview and inpatient chart review

Exclusion Criteria:

  • Psychotic symptoms, as assessed using the Mini International Neuropsychiatric Interview and inpatient chart review
  • Cognitive disorder, assessed using a six-item cognitive screen developed for research
  • Primary admission diagnosis of substance use disorder
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01820286

Locations
United States, Massachusetts
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Sponsors and Collaborators
Massachusetts General Hospital
Investigators
Principal Investigator: Jeff C Huffman, MD Massachusetts General Hospital
  More Information

No publications provided

Responsible Party: Jeff C. Huffman, MD, Medical Director of Inpatient Psychiatric Unit, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT01820286     History of Changes
Other Study ID Numbers: 2012P002294
Study First Received: March 25, 2013
Last Updated: August 7, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by Massachusetts General Hospital:
Bipolar disorder
Depression
Positive psychology

Additional relevant MeSH terms:
Bipolar Disorder
Depression
Depressive Disorder
Disease
Mood Disorders
Affective Disorders, Psychotic
Behavioral Symptoms
Mental Disorders
Pathologic Processes

ClinicalTrials.gov processed this record on October 20, 2014