Twentyfour Ambulatory Pulse Wave Velocity and Central Augmentation Index in Type 2 Diabetes
The functionality and reproducibility of pulse wave analysis is investigated in 20 type 2 diabetic patients who had two 24 hour measurements performed within one week with the Arteriograph24 equipment.
Type 2 Diabetes
|Study Design:||Time Perspective: Prospective|
|Official Title:||Twentyfour Ambulatory Pulse Wave Velocity and Central Augmentation Index in Type 2 Diabetes|
- Fraction of missed pulse wave analysis [ Time Frame: Meaured two times with an interval of one week ] [ Designated as safety issue: No ]Measurements of ambulatory blood pressure and pulse wave analysis is performed every twenty minute. The fraction of missed measurements of pulse wave analysis during day time and night time analysis is the final outcome
- Reproducibility of pulse wave analysis parameters [ Time Frame: Measured two times with an interval of one week ] [ Designated as safety issue: No ]Reproducibility of pulse wave velocity, Central systolic blood pressure and central augmentation index for 24 hour, day and night
- Diurnal variation of brachial blood pressure, central blood pressure and pulse wave velocity [ Time Frame: Measured two times with an interval of one week ] [ Designated as safety issue: No ]brachial blood pressure, central blood pressure and pulse wava velocity is measured evrey twenty minutes and averaged for day time and night time. the relative reduction at nioght for the parameters are calculated
|Study Start Date:||September 2012|
|Study Completion Date:||July 2013|
|Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
Arteriograph24 is a new monitor for measuring ambulatory blood pressure and additional performing brachial cuff based on analysis of a suprasystolic pulse wave.
The study aim to test the feasibility of ambulatory pulse wave analysis every twenty minute (the fraction of missed measurements)and the reprodicility of pulse wave velocity and central augmentation index in type 2 diabetic patients. In addition we will explore the relation between diurnal variation of brachial blood pressure, central blood pressure and pulse wave velocity.
20 type 2 diabetic patients will have 24h ambulatory blood pressure performed twice with an interval of one week.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01812811
|Medical department, Diagnostic Center, Regional Hospital Silkeborg|
|Silkeborg, Denmark, 8600|
|Principal Investigator:||Klavs W Hansen, MD, dr.med.||Medical department, Diagnostic Center, Regional Hospital Silkeborg, Denmark|