A Nested Case-control Study on the Secondary Prevention of Ischemic Stroke and TIA by Hypertension Health Education Protocol (HHEP): The Post-Stroke Preventive Trial
Patients with a diagnosis of ischemic stroke or TIA (ISTIA), who are treated at hospital are asked to participate in our pre specified hypertension health education protocol (HHEP) after discharge from our hospital.HHEP was used as secondary prevention treatments of stroke and cardiovascular diseases.
HHEP consists of several items such as controlling the patient's hypertension level, monitoring the adherece of antihypertensive agents, reducing risk factors of hytertension like tobacco smoking, obesity, and motivating the patient to physical activity and to a healthy diet.
Patients will receive visits by a study nurse with the aim of supervising, monitoring, and recording the adherence of HHEP. The patients will be classified as different adherence level at the end of the study according to their adherence condition.
This study is aimed at testing the hypothesis that controlling hypertension and its risk factors was more effective than those do not receive HHEP in reducing the recurrence of stroke and cardiovascular diseases.
To Investigate the Relationship Between the Adherence of HHEP After ISTIA and Stroke Recurrence or Cardiovascular Events.
Other: Hypertension Health Education Protocol (HHEP)
|Study Design:||Masking: Open Label
Primary Purpose: Prevention
- Nonfatal vascular events: ischemic or hemorrhagic stroke recurrence (ICD-9 431 or ICD-10 I61), or myocardial infarction(MI) (ICD-9 410 or ICD-10 I21). [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- vascular death (death within 30 days after a vascular event) and all-cause mortality. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
|Study Start Date:||April 2013|
|Estimated Primary Completion Date:||April 2015 (Final data collection date for primary outcome measure)|
|Experimental: Ischemic Stroke or TIA (ISTIA) patients||Other: Hypertension Health Education Protocol (HHEP)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01812421
|Contact: YeFeng Cai, Dr.||email@example.com|
|Brain Center,Guangdong Province Hospital of Traditional Chinese Medicine||Recruiting|
|Guangzhou, Guangdong, China, 510120|
|Contact: YeFeng Cai, Dr. firstname.lastname@example.org|
|Sub-Investigator: ZiYi Zhou, Master|
|Sub-Investigator: Lin Wei, Master|
|Sub-Investigator: XiaoPei Zhang, Master|