Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Hasselt University
Sponsor:
Collaborator:
Ziekenhuis Oost-Limburg
Information provided by (Responsible Party):
Cornelia Genbrugge, Hasselt University
ClinicalTrials.gov Identifier:
NCT01806844
First received: March 6, 2013
Last updated: June 2, 2014
Last verified: June 2014
  Purpose

Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be measured. By applying the Beer-Lamber law, a numeric result can be calculated. During a cardiac arrest, there is no stroke volume, no cardiac output and no cerebral perfusion. By using cerebral NIRS during out-of hospital cardiac arrest, low flow time and return of spontaneous circulation, this study wants to show the prognostic value of NIRS as extra monitoring.


Condition
Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cerebral Oxygenation During Resuscitation and Post-resuscitation Phase

Resource links provided by NLM:


Further study details as provided by Hasselt University:

Primary Outcome Measures:
  • prognostic value [ Time Frame: 1 year ] [ Designated as safety issue: No ]
    Prognostic value of cerebral oxygenation during CPR


Estimated Enrollment: 200
Study Start Date: May 2013
Estimated Primary Completion Date: May 2015 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   16 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

pre-hospital cardiac arrest

Criteria

Inclusion Criteria:

  • >16 year

Exclusion Criteria:

  • DNR code
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01806844

Contacts
Contact: Cornelia Genbrugge, MD cornelia.genbrugge@uhasselt.be

Locations
Belgium
Ziekenhuis Oost-Limburg Recruiting
Genk, Limburg, Belgium, 3600
Contact: Cornelia Genbrugge, MD       cornelia.genbrugge@uhasselt.be   
Principal Investigator: Cornelia Genbrugge, MD         
Sub-Investigator: Cathy De Deyne, MD. PhD         
Sub-Investigator: Jo Dens, MD. PhD         
Universitair ziekenhuis Leuven Not yet recruiting
Leuven, Vlaams Brabant, Belgium, 3000
Contact: Marc Sabbe, MD PhD       marc.sabbe@uzleuven.be   
Contact: Cornelia genbrugge         
GZA St Vincentius Active, not recruiting
Antwerp, Belgium
Ziekenhuis netwerk Antwerpen Recruiting
Antwerpen, Belgium, 2000
Contact: Cornelia Genbrugge, MD         
AZ Turnhout Recruiting
Turnhout, Belgium
Contact: Dr. Mertens, MD         
Sub-Investigator: Ilse Mertens         
Sponsors and Collaborators
Hasselt University
Ziekenhuis Oost-Limburg
Investigators
Principal Investigator: Cornelia Genbrugge, MD Hasselt University
  More Information

Publications:
Responsible Party: Cornelia Genbrugge, Dr. Genbrugge, Hasselt University
ClinicalTrials.gov Identifier: NCT01806844     History of Changes
Other Study ID Numbers: Copernicus I
Study First Received: March 6, 2013
Last Updated: June 2, 2014
Health Authority: Belgium: Ethics Committee

Keywords provided by Hasselt University:
Cardiac arrest
Cerebral oxygenation
Pre-hospital

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 29, 2014