Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)

This study is currently recruiting participants.
Verified October 2013 by Hasselt University
Sponsor:
Collaborator:
Ziekenhuis Oost-Limburg
Information provided by (Responsible Party):
Cornelia Genbrugge, Hasselt University
ClinicalTrials.gov Identifier:
NCT01806844
First received: March 6, 2013
Last updated: October 15, 2013
Last verified: October 2013
  Purpose

Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be measured. By applying the Beer-Lamber law, a numeric result can be calculated. During a cardiac arrest, there is no stroke volume, no cardiac output and no cerebral perfusion. By using cerebral NIRS during out-of hospital cardiac arrest, low flow time and return of spontaneous circulation, this study wants to show the prognostic value of NIRS as extra monitoring.


Condition
Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cerebral Oxygenation During Resuscitation and Post-resuscitation Phase

Resource links provided by NLM:


Further study details as provided by Hasselt University:

Primary Outcome Measures:
  • prognostic value [ Time Frame: 1 year ] [ Designated as safety issue: No ]
    Prognostic value of cerebral oxygenation during CPR


Estimated Enrollment: 200
Study Start Date: May 2013
Estimated Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   16 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

pre-hospital cardiac arrest

Criteria

Inclusion Criteria:

  • >16 year

Exclusion Criteria:

  • DNR code
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01806844

Contacts
Contact: Cornelia Genbrugge, MD cornelia.genbrugge@uhasselt.be

Locations
Belgium
Ziekenhuis Oost-Limburg Recruiting
Genk, Limburg, Belgium, 3600
Contact: Cornelia Genbrugge, MD       cornelia.genbrugge@uhasselt.be   
Principal Investigator: Cornelia Genbrugge, MD         
Sub-Investigator: Cathy De Deyne, MD. PhD         
Sub-Investigator: Jo Dens, MD. PhD         
Universitair ziekenhuis Leuven Not yet recruiting
Leuven, Vlaams Brabant, Belgium, 3000
Contact: Marc Sabbe, MD PhD       marc.sabbe@uzleuven.be   
Contact: Cornelia genbrugge         
Ziekenhuis netwerk Antwerpen Recruiting
Antwerpen, Belgium, 2000
Contact: Cornelia Genbrugge, MD         
Sponsors and Collaborators
Hasselt University
Ziekenhuis Oost-Limburg
Investigators
Principal Investigator: Cornelia Genbrugge, MD Hasselt University
  More Information

Publications:
Responsible Party: Cornelia Genbrugge, Dr. Genbrugge, Hasselt University
ClinicalTrials.gov Identifier: NCT01806844     History of Changes
Other Study ID Numbers: Copernicus I
Study First Received: March 6, 2013
Last Updated: October 15, 2013
Health Authority: Belgium: Ethics Committee

Keywords provided by Hasselt University:
Cardiac arrest
Cerebral oxygenation
Pre-hospital

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on April 20, 2014