Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm
Test single nucleotide polymorphisms (SNP's) in ruptured and unruptured aneurysm tissue to identify a genetic difference between the two types of aneurysms; and to test SNP's in arteriovenous malformation tissue to identify a genetic link.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm|
- Risk gene expression [ Time Frame: Within one week of sample collection. ] [ Designated as safety issue: No ]The samples will be frozen after collection and then analyzed.
Biospecimen Retention: Samples With DNA
Tissue samples of intracranial arterial-venous malformations (AVM) or aneurysm and blood samples.
|Study Start Date:||November 2011|
|Estimated Primary Completion Date:||November 2014 (Final data collection date for primary outcome measure)|
Patients receiving surgical intervention for an intracranial arterial-venous malformation.
Patients receiving surgical intervention for a ruptured intracranial aneurysm.
Patients receiving surgical intervention for an unruptured intracranial aneurysm.
|Contact: Mark R Villwock, MSfirstname.lastname@example.org|
|United States, New York|
|SUNY Upstate Medical University||Recruiting|
|Syracuse, New York, United States, 13210|
|Contact: Mark R Villwock, MS 315-464-5502 email@example.com|
|Principal Investigator:||Eric M Deshaies, MD||SUNY Upstate Medical University Neurosurgery|