Oxygen Level and Safe Emergence From Anesthesia
Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.
Focus of Study is Postoperative Pulmonary Atelectacis
Procedure: 30% oxygen
Procedure: 100% oxygen
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Prevention
|Official Title:||Emergence From General Anesthesia With Laryngeal Mask Airway and Increased End-expiratory Pressure Using 30% Oxygen is as Safe as With 100% Oxygen But Reduces the Area of Post Operative Atelectasis.|
- Area of atelectasis [ Time Frame: 30 minutes ] [ Designated as safety issue: Yes ]The area of atelectasis is investigated by computed tomography of the lungs postoperatively
- Peripheral oxygen saturation (SpO2) [ Time Frame: 3 hours ] [ Designated as safety issue: Yes ]SpO2 is continuously assessed postoperatively.
|Study Start Date:||February 2013|
|Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
Experimental: 100% oxygen during extubation
In this arm the intervention will consist of 100 % oxygen.
|Procedure: 100% oxygen|
Experimental: 30% oxygen during extubation
In this arm the intervention will consist of 30 % oxygen.
|Procedure: 30% oxygen|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01779076
|Västmanlands sjukhus Köping|
|Köping, Västmanland, Sweden, 731 81|
|Principal Investigator:||Mats Enlund, M.D., Ph.D.||Landstinget i Värmland|