Effect of Follicular Phase Acupuncture on Anti-Mullerian Hormone in Polycystic Ovary Syndrome (PCOS) Patients Undergoing IVF And The Effect on Assisted Reproduction Outcome
Acupuncture at follicular phase of the cycle may improve the pregnancy rate. This study aims to compare assisted reproduction outcome between two groups of infertile PCOS patients underwent IVF, one group received acupuncture and other group without acupuncture.
Effect of Acupuncture on Infertile PCOS Patients.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Acupuncture Treatment Versus Non-acupuncture During IVF|
- Clinical pregnancy rate. [ Time Frame: 13 months ] [ Designated as safety issue: No ]
- Ongoing pregnancy rate [ Time Frame: 15 months ] [ Designated as safety issue: No ]
|Study Start Date:||March 2011|
|Study Completion Date:||May 2012|
|Primary Completion Date:||March 2012 (Final data collection date for primary outcome measure)|
Experimental: Acupuncture (Hwato®)
30-40 minutes acupuncture at certain acupoints that chosen according to traditional Chinese medicine and included LIV3,SP6,SP8,ST36,SP10,ST29,LI14,Ren 04;starting at follicular phase of the cycle till 2 days before oocyte picked up.
acupuncture using 4cm long disposable stainless steel hair-thin needles manufactured by Suzhou medical appliance factory (China).
No Intervention: No acupuncture
No intervention was done for this group of patients.
Follicular phase acupuncture applied for infertile PCOS patients underwent IVF to evaluate the effect of acupuncture on anti-mullerian hormone (AMH) and the effect on assisted reproduction outcome. It applied at certain acupoints according to the principles of traditional Chinese medicine.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01778621
|Assisted Reproduction Center, Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology|
|Wuhan, Hubei, China, 430022|
|Study Director:||Ying Gao, Ph.D., M.D.||Assisted Reproduction Center, Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology|