Speech Intelligibility of Patients With P D Compared to First Degree Relatives of P D Patients
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Purpose
This study will examine speech intelligibility of early parkinson's disease (PD) patients, early PD patients and first degree relatives. The investigators hypothesis that advanced PD patients will present decreased speech intelligibility more than early PD patients. Speech intelligibility of first degree relatives will be normal.
| Condition |
|---|
|
Parkinson's Disease |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Speech Intelligibility of Patients With Parkinsons Disease at Different Stages of the Disease Compared to First Degree Relatives of Parkinson's Disease Patients |
- Maximum phonation time [ Time Frame: DAY 1 ] [ Designated as safety issue: No ]maximum phonation time will be measured after taking few measurements of sentence reading.It is an observational study that aim to collect data during DAY 1 only! day 1 for outcome measure time frames There are not pre/post measurements
- Diadokokinetik (DDK): production time of 10x PATAKA, 7x /P/ and 7x /t/ [ Time Frame: DAY 1 ] [ Designated as safety issue: No ]
production time of 10x PATAKA, 7x /P/ and 7x /t/ will be measured during the examination.
It is an observational study that aim to collect data during DAY 1 only! DAY 1 for outcome measure time frames There are not pre/post measurements
| Estimated Enrollment: | 60 |
| Study Start Date: | February 2013 |
| Estimated Study Completion Date: | November 2014 |
| Estimated Primary Completion Date: | November 2013 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
early & advanced PD 1st degree relatives
no intervention is performed in the study
|
|
recording speech and voice
no intervention(s) will be administered
|
|
speech intelligibility
no intervention(s) will be administered
|
Detailed Description:
in order to achieve the study's goals objective and subjective research tools will be used.
Objective tools include measuring phonation time, diadokokinetic movements of the oral structures and acoustic analysis .
Subjective tools include self reported questionnaires.
Eligibility| Ages Eligible for Study: | 20 Years to 90 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Advanced PD patients Early PD patients First degree relatives
Inclusion Criteria:A
- Advanced PD patients
- Early PD patients
- First degree relatives
Exclusion Criteria:
- Patients with decreased cognitive abilities
- Patients who participate in speech therapy
Contacts and Locations| Contact: Tanya Gurevich, MD | 97236973061 | gurevich@tasmc.health.gov.il |
| Contact: Yael Manor, PhD | 97236973061 | Yaelm@tasmc.health.gov.il |
| Principal Investigator: | Tanya Gurevich, MD | Tel-Aviv Sourasky Medical Center |
More Information
No publications provided
| Responsible Party: | Michal Roll PhD,MBA, director rnd devision, Tel-Aviv Sourasky Medical Center |
| ClinicalTrials.gov Identifier: | NCT01776879 History of Changes |
| Other Study ID Numbers: | TASMC-12-TG-0556-CTIL, 0556-12 |
| Study First Received: | November 13, 2012 |
| Last Updated: | January 23, 2013 |
| Health Authority: | Israel: Ethics Commission |
Additional relevant MeSH terms:
|
Parkinson Disease Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases |
Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases |
ClinicalTrials.gov processed this record on May 21, 2013