Comparison of Insulin Mix25 Versus Mix50 (CLASSIFY)

Inclusion Criteria:

• Have a diagnosis of Type 2 Diabetes Mellitus for at least 6 months
• Have been taking sulfonylureas, biguanide, thiazolidinedione, alpha-glucosidase inhibitor, glinide, or dipeptidyl peptidase IV inhibitor, or any combination of these
• Have a qualifying hemoglobin A1c value ≥7.0% and ≤11.0% at screening
• Have a body mass index (BMI) ≥18.5 and <35.0 kilogram per square meter (kg/m^2)
• Have given written informed consent to participate in the study in accordance with local regulations and the ethical review board (ERB) governing the study site

Exclusion Criteria:

• Have a diagnosis of type 1 diabetes
• Have had more than 1 episode of severe hypoglycemia within the 6 months before screening
• Have any of the following cardiovascular conditions within 3 months prior to screening: acute myocardial infarction, New York Heart Association class III or class IV heart failure, or cerebrovascular accident (stroke)
• Have obvious clinical signs or symptoms of liver disease, acute or chronic hepatitis, or alanine aminotransferase levels ≥3.0 times the upper limit of the reference range at screening, as determined by the central laboratory
• Have an estimated creatinine clearance (CrCl), Cockcroft-Gault formula <30 milliliter per minute (mL/min), as determined by the central laboratory at screening
• Have evidence of a significant, active, uncontrolled endocrine or autoimmune abnormality, as judged by the investigator
• Have an active or untreated malignancy or have been in remission from a clinically significant malignancy for <5 years
• Have any other condition (such as, known drug or alcohol abuse or a psychiatric disorder) that may prevent the participants from following and completing the protocol
• Are currently enrolled in, or discontinued within the last 30 days from, a clinical trial involving an investigational product or non-approved use of a drug or device, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study