Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

This study is enrolling participants by invitation only.
Sponsor:
Information provided by (Responsible Party):
Montana Compton, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT01771718
First received: January 15, 2013
Last updated: July 31, 2014
Last verified: July 2014
  Purpose

The researchers wants to use the multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin. Currently, there is no standard non-invasive method for skin imaging. Researchers of the Beckman Laser Institute (BLI) have developed many non-invasive imaging modalities for assessment of skin. In this study, a multiphoton tomograph (MPM/MPTflex) will be used for assessment of skin.


Condition Intervention
Skin Lesion
Device: multiphoton microscopy.

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Pilot Study on In-vivo Non-invasive Skin Imaging Using MPM

Further study details as provided by University of California, Irvine:

Primary Outcome Measures:
  • Non-invasive Skin Imaging [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]
    Non-invasive Skin Imaging


Estimated Enrollment: 20
Study Start Date: April 2012
Estimated Study Completion Date: June 2016
Estimated Primary Completion Date: June 2016 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Image parameters for MPM
qualitative image parameters for evaluating the clinical applicability of multiphoton microscopy.
Device: multiphoton microscopy.
multiphoton microscopy.

Detailed Description:

The researchers want to know differences between pigmented and non-pigmented skin areas, such as the presence of melanocytes and the pattern of collagen and elastin networks. Benign and cancerous skin lesions will be imaged and evaluated using the MPM/MPTflex device. The intent is to differentiate benign and cancerous skin lesions without a biopsy, using this non-invasive skin imaging method.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

primary care clinic

Criteria

Inclusion Criteria:

  • Male or Female age 18 years of age or older
  • Has diagnose with skin pigmented lesion

Exclusion Criteria:

  • Minor and pregnant women
  • Has no pigmented lesion
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01771718

Locations
United States, California
Beckman Laser Institute Medical Clinic
Irvine, California, United States, 92612
Sponsors and Collaborators
Montana Compton
Investigators
Principal Investigator: Kristen Kelly, MD Beckman Laser Institute, UCI
  More Information

No publications provided

Responsible Party: Montana Compton, Research Nurse, University of California, Irvine
ClinicalTrials.gov Identifier: NCT01771718     History of Changes
Other Study ID Numbers: ROI-29410
Study First Received: January 15, 2013
Last Updated: July 31, 2014
Health Authority: United States: Institutional Review Board

ClinicalTrials.gov processed this record on August 27, 2014