Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
The researchers wants to use the multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin. Currently, there is no standard non-invasive method for skin imaging. Researchers of the Beckman Laser Institute (BLI) have developed many non-invasive imaging modalities for assessment of skin. In this study, a multiphoton tomograph (MPM/MPTflex) based on the MPM technology will be used for assessment of skin.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Pilot Study on In-vivo Non-invasive Skin Imaging Using MPM|
- Non-invasive Skin Imaging [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]Non-invasive Skin Imaging
|Study Start Date:||April 2012|
|Estimated Study Completion Date:||June 2016|
|Estimated Primary Completion Date:||June 2016 (Final data collection date for primary outcome measure)|
Image parameters for MPM
qualitative image parameters for evaluating the clinical applicability of multiphoton microscopy.
Device: multiphoton microscopy.
The researchers wants to kown about the changes of the pigmented skin with respect to non-pigmented skin areas, the presence of melanocytes in the superficial epidermal layers and the pattern of the collagen and elastin networks. The skin will be imaged using the MPM/MPTflex device.
Subject who will be seen by their physician at Beckman Laser Institute Medical clinic will be selected to participate in this study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01771718
|United States, California|
|Beckman Laser Institute Medical Clinic|
|Irvine, California, United States, 92612|
|Principal Investigator:||Kristen Kelly, MD||Beckman Laser Institute, UCI|