Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
The researchers wants to use the multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin. Currently, there is no standard non-invasive method for skin imaging. Researchers of the Beckman Laser Institute (BLI) have developed many non-invasive imaging modalities for assessment of skin. In this study, a multiphoton tomograph (MPM/MPTflex) based on the MPM technology will be used for assessment of skin.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Pilot Study on In-vivo Non-invasive Skin Imaging Using MPM|
- Non-invasive Skin Imaging [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]Non-invasive Skin Imaging
|Study Start Date:||April 2012|
|Estimated Study Completion Date:||June 2016|
|Estimated Primary Completion Date:||June 2016 (Final data collection date for primary outcome measure)|
Image parameters for MPM
qualitative image parameters for evaluating the clinical applicability of multiphoton microscopy.
Device: multiphoton microscopy.
The researchers wants to kown about the changes of the pigmented skin with respect to non-pigmented skin areas, the presence of melanocytes in the superficial epidermal layers and the pattern of the collagen and elastin networks. The skin will be imaged using the MPM/MPTflex device.
Subject who will be seen by their physician at Beckman Laser Institute Medical clinic will be selected to participate in this study.
|United States, California|
|Beckman Laser Institute Medical Clinic|
|Irvine, California, United States, 92612|
|Principal Investigator:||Kristen Kelly, MD||Beckman Laser Institute, UCI|