Effect of Sweetness of the Beverage in Thirst Sensation

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Pedro Miguel Fernandes Ramos de Carvalho, Universidade do Porto
ClinicalTrials.gov Identifier:
NCT01771094
First received: January 15, 2013
Last updated: NA
Last verified: January 2013
History: No changes posted
  Purpose

The purpose of this study is to determine if water and diet soft drinks with different levels of sweeteners have the same effect on thirst.


Condition Intervention
Thirst
Behavioral: Effect of sweetness of the beverage in thirst sensation

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Diagnostic
Official Title: Effect of Sweetness of the Beverage in Thirst Sensation

Resource links provided by NLM:


Further study details as provided by Universidade do Porto:

Primary Outcome Measures:
  • Motivational Ratings [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    Participants will rate their hunger, thirst, nausea, mouth dryness, desire to eat, desire to drink using nine point category scales. The unipolar adjective scales were anchored at each end with labels: 1 = not at all and 9 = extremely. Participants also rated their perception about beverage sweetness along nine point hedonic preference scales where 1 = no sweet at all and 9 = extremely sweet


Secondary Outcome Measures:
  • Food Behavior After Intervention [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    After lunch, participants will bring a food diary to record all food and fluid intake until 00.00 that day. Then, we will analyse total calories ingested, total fluid ingested and the volume of sugar and sugary beverages ingested.

  • Physiological Parameters [ Time Frame: 1 day ] [ Designated as safety issue: Yes ]
    Glycaemia, blood osmolality and hydration parameters (total body water, intra and extracellular body water) will be assessed before and after the ingestion of beverages

  • Amount of water ingested [ Time Frame: 1 day ] [ Designated as safety issue: No ]
    After the ingestion of 3 preloads with the beverages in study, the participants will lunch the same meal with free water ingestion


Enrollment: 27
Study Start Date: February 2012
Study Completion Date: March 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Placebo Comparator: Group 1 (placebo) - Water
This group will drink water in 1st trial
Behavioral: Effect of sweetness of the beverage in thirst sensation

Effect of sweetness of the beverage in thirst sensation:

The participants will drink Water (control group),"High Sucralose" - Decarbonized Pineapple Diet Soda with a 50% increase of sucralose face to standard beverage, and "Low Sucralose" - Decarbonized Pineapple with a 50% decrease of sucralose face to standard beverage. The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min.

Experimental: Group 3 (Intervention) - "Low" Sucralose
This group will drink Decarbonized Pineapple with a 50% decrease of sucralose face to standard beverage in 1st trial
Behavioral: Effect of sweetness of the beverage in thirst sensation

Effect of sweetness of the beverage in thirst sensation:

The participants will drink Water (control group),"High Sucralose" - Decarbonized Pineapple Diet Soda with a 50% increase of sucralose face to standard beverage, and "Low Sucralose" - Decarbonized Pineapple with a 50% decrease of sucralose face to standard beverage. The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min.

Experimental: Group 2(Intervention)-"High" Sucralose
This group will drink Decarbonized Pineapple Diet Soda with a 50% increase of sucralose face to standard beverage in 1st trial
Behavioral: Effect of sweetness of the beverage in thirst sensation

Effect of sweetness of the beverage in thirst sensation:

The participants will drink Water (control group),"High Sucralose" - Decarbonized Pineapple Diet Soda with a 50% increase of sucralose face to standard beverage, and "Low Sucralose" - Decarbonized Pineapple with a 50% decrease of sucralose face to standard beverage. The beverages will be presented chilled but without ice in 500 ml portions in opaque plastic containers and participants will be asked to consume the entire amount within 15 min.


Detailed Description:

Participants should be in the laboratory at 8.00 in order to collect the values of weight, height, total body water, intracellular water and extracellular water in a Segmental Multi Frequency Body Composition Monitor (TANITA MC 180 MA®). Then, a blood sample will be collected for analysis of blood glucose and osmolality. They will sit at individual tables for the duration of the session and were allowed to read, listen to music with earphones, or use their portable computers with the exception of internet access to minimize visual cues (e.g., unwanted publicity for beverages or visiting Web sites showing pictures of food and drinks), which may have effect on thirst. Breakfast will be served at 9.30 on every occasion and preload stimuli will be offered exactly 60 minutes after breakfast (at 10.30). Lunch will be provided at 13.00. Motivational ratings will be first obtained at the end of collection of blood sample (baseline or time 0) and every 30 minutes thereafter until the lunch time (times 1 through 7). After lunch (time 8), participants will complete the last set of ratings and will bring a food diary to record all food and fluid intake until 00.00 that day.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Exclusion Criteria:

  • pregnant and nursing women
  • smokers
  • athletes
  • subjects under medication(except oral contraceptives in women)

Inclusion Criteria:

  • body mass index(BMI) between (18,5 - 27,5 kg/m2)
  • regular consumers of breakfast
  • stable in weight for the past 6 months
  • not dieting to gain or lose weight
  • like all drinks and food available in study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01771094

Locations
Portugal
Faculty of Nutrition and Food Sciences - University of Porto
Porto, Portugal, 4200-465
Sponsors and Collaborators
Universidade do Porto
Investigators
Principal Investigator: Pedro R Carvalho, PhD Student FCNAUP
  More Information

No publications provided

Responsible Party: Pedro Miguel Fernandes Ramos de Carvalho, Invited Assistant, Universidade do Porto
ClinicalTrials.gov Identifier: NCT01771094     History of Changes
Other Study ID Numbers: IHS/FCNAUP-002, Nº30/CEUP/2011
Study First Received: January 15, 2013
Last Updated: January 15, 2013
Health Authority: Portugal: Health Ethic Committee

ClinicalTrials.gov processed this record on April 15, 2014