Impact of Culture Conditions on the Embryo Quality

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Thomas D'Hooghe, University Hospital, Gasthuisberg
ClinicalTrials.gov Identifier:
NCT01767805
First received: January 8, 2013
Last updated: January 10, 2013
Last verified: January 2013
  Purpose

The purpose of this study is to compare different culture conditions. The effect of the type of incubator (standard versus mini-incubator) and the effect of the oxygen concentration (5% versus 20%) will be evaluated on the embryo quality


Condition Intervention
Embryo Development
Procedure: Standard incubator
Procedure: Mini incubator
Procedure: 5% oxygen
Procedure: 20% oxygen

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Basic Science

Resource links provided by NLM:


Further study details as provided by University Hospital, Gasthuisberg:

Primary Outcome Measures:
  • embryo quality [ Time Frame: day 1- day 3 ] [ Designated as safety issue: Yes ]

Enrollment: 790
Study Start Date: June 2009
Study Completion Date: September 2011
Primary Completion Date: September 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Type of incubator
Embryos are cultured in a standard incubator or a mini-incubator
Procedure: Standard incubator Procedure: Mini incubator
Oxygen concentration
Embryos are cultured in an incubator with a gas mixture with 20% oxygen or with 5% oxygen
Procedure: 5% oxygen Procedure: 20% oxygen

  Eligibility

Ages Eligible for Study:   up to 3 Days
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • embryos of patients younger than 36 years old

Exclusion Criteria:

  • embryos of patients older than 36 years old
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01767805

Locations
Belgium
University Hospital Leuven, Catholic University Leuven
Leuven, Belgium
University Hospital Leuven, Catholic University Leuven
Leuven, Belgium, 3000
Sponsors and Collaborators
University Hospital, Gasthuisberg
  More Information

No publications provided

Responsible Party: Thomas D'Hooghe, Prof. Dr., University Hospital, Gasthuisberg
ClinicalTrials.gov Identifier: NCT01767805     History of Changes
Other Study ID Numbers: ML4563
Study First Received: January 8, 2013
Last Updated: January 10, 2013
Health Authority: Belgium: Federale Commissie voor medisch en wetenschappelijk onderzoek op embryo's in vitro

ClinicalTrials.gov processed this record on July 20, 2014