Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Cohort)

This study is currently recruiting participants. (see Contacts and Locations)
Verified January 2013 by Centre Hospitalier Universitaire Dijon
Sponsor:
Information provided by (Responsible Party):
Centre Hospitalier Universitaire Dijon
ClinicalTrials.gov Identifier:
NCT01766596
First received: January 10, 2013
Last updated: NA
Last verified: January 2013
History: No changes posted
  Purpose

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.

The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.


Condition Intervention
AMD
Glaucoma
Procedure: Optical Coherence Tomography

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging

Resource links provided by NLM:


Further study details as provided by Centre Hospitalier Universitaire Dijon:

Primary Outcome Measures:
  • Measure the mean thickness of postganglionic fibers [ Time Frame: T=7 years of the 3C cohort ]
    Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.


Estimated Enrollment: 3000
Study Start Date: October 2009
Estimated Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
3C cohort Procedure: Optical Coherence Tomography

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Persons who have given their written consent
  • Persons who are taking part in the Dijon 3C study

Exclusion Criteria:

  • Persons who are not registered with social security agency
  • Persons who are unable to sit upright during a consultation
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01766596

Contacts
Contact: Catherine CREUZOT-GARCHER 3 80 29 51 73 ext 33 catherine.creuzot-garcher@chu-dijon.fr

Locations
France
CHU Dijon Recruiting
Dijon, France, 21000
Contact: Catherine CREUZOT-GARCHER    3 80 29 51 73 ext 33    catherine.creuzot-garcher@chu-dijon.fr   
Principal Investigator: Catherine CREUZOT-GARCHER         
Sub-Investigator: Alain BRON         
Sub-Investigator: Marie PASSEMARD         
Sponsors and Collaborators
Centre Hospitalier Universitaire Dijon
  More Information

No publications provided

Responsible Party: Centre Hospitalier Universitaire Dijon
ClinicalTrials.gov Identifier: NCT01766596     History of Changes
Other Study ID Numbers: Creuzot-Garcher PHRC IR 2009
Study First Received: January 10, 2013
Last Updated: January 10, 2013
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by Centre Hospitalier Universitaire Dijon:
Ophthalmology
Age-related ocular pathologies

Additional relevant MeSH terms:
Glaucoma
Ocular Hypertension
Eye Diseases

ClinicalTrials.gov processed this record on August 26, 2014