Tumor Bank for Blood Samples

This study is currently recruiting participants. (see Contacts and Locations)
Verified November 2013 by Medical University of Vienna
Sponsor:
Information provided by (Responsible Party):
Univ.Prof.Dr. Robert Zeillinger, Medical University of Vienna
ClinicalTrials.gov Identifier:
NCT01763125
First received: January 4, 2013
Last updated: November 14, 2013
Last verified: November 2013
  Purpose

Establishment of a tumor bank, consisting of blood samples of tumor patients and healthy people as controls. The blood samples will be collected systematically together with the corresponding clinical data. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tumor bank.


Condition Intervention
Ovarian Neoplasms
Breast Neoplasms
Colorectal Neoplasms
Neoplasms of the Female Genitalia
Lung Neoplasms
Endocrine Gland Neoplasms
Other: Blood collection

Study Type: Observational
Study Design: Observational Model: Case Control
Official Title: Establishment of a Blood Sample Bank in the Field of Gynaecological Oncology.

Resource links provided by NLM:


Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Establishment of blood/tissue bank consisting of oncological samples from cancer patients and benign and healthy controls. [ Time Frame: 14 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Universal tumor bank


Estimated Enrollment: 10000
Study Start Date: November 2003
Estimated Study Completion Date: January 2017
Estimated Primary Completion Date: January 2017 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Malignant tumors
Patients who have one of the Neoplasms stated above under "conditions". Blood samples will be taken.
Other: Blood collection
Blood sample is collected during routine blood collection by a medical doctor. No more than 60ml (max.) at one timepoint.
Benign controls

Patients with a benign tumor or an inflammatory disease - to be matched by age and affected organ with a patient with a malignant disease.

Blood samples will be taken.

Other: Blood collection
Blood sample is collected during routine blood collection by a medical doctor. No more than 60ml (max.) at one timepoint.
Healthy controls

People/patients who have no known disease at time of blood sampling or are admitted to the hospital for minor interventions and have no inflammatory disease.

Blood samples will be taken.

Other: Blood collection
Blood sample is collected during routine blood collection by a medical doctor. No more than 60ml (max.) at one timepoint.

Detailed Description:

Recent progress in diagnosis and therapy of cancer diseases can be ascribed mainly to translational research. The relevance of "translational oncology" will only increase in the future -"From bench to bedside" - the swift implementation of new science research results in clinical studies in order to expedite progress in clinical cancer therapy for the benefit of the patient.

Its almost a matter of course in the medical science today to collect biological samples together with clinical information thereby creating the foundation for future excellent fundamental research.

The aim of this tumor bank is to consist of biological samples (together with a tissue bank - see EK 260/2003) and isolates of tumor patients and healthy people as controls. The biological samples, the clinical date together with prospective experimental date constitute the entity of the tumor bank. The content of the tumor bank can provide essential material for current and future research (e.g. analyses of prognostic or predictive tumor markers; genetically analysis (polymorphism, mutation, hypermethylation; verification and characterisation of disseminated tumor cells).

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
  • Male and female patients/people.
  • Minimum age 18 years
  • Characteristics: Recruited at the Medical University Vienna or at one of the facilities cooperating with the Vienna Med. University
Criteria

Inclusion Criteria:

  • Male/Female
  • Age 18 to 90 years max.
  • Just one current known malignant disease or
  • Just one current inflammatory disease

Exclusion Criteria:

  • Inflammatory disease and malignant disease
  • multiple malignancies
  • multiple diseases
  • underage
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01763125

Contacts
Contact: Robert Zeillinger, Prof. Dr. +43140400 ext 7831 robert.zeillinger@meduniwien.ac.at
Contact: Nina Pecha +43140400 ext 2784 nina.pecha@meduniwien.ac.at

Locations
Austria
Innsbruck Medical University Not yet recruiting
Innsbruck, Austria, 6020
Contact: Nicole Concin, Prof.Dr.    +43 50-504-0    nicole.concin@i-med.ac.at   
Belgium
University Hospitals Leuven - Department of Obstetrics and Gynaecology Recruiting
Leuven, Belgium, 3000
Contact: Ignace Vergote, Prof.Dr.    +32/1634 ext 4208    ignace.vergote@uzleuven.be   
Contact: Joke de Roover    +32 16 34 ext 74 19    joke.deroover@uz.kuleuven.ac.be   
Czech Republic
University Hospital Motol, Charles University, Dpt of Obstet. & Gynaec. Active, not recruiting
Praha, Czech Republic, 5 15006
Germany
Charité University - Campus Virchow Chlinic Recruiting
Berlin, Germany, 13353
Contact: Jalid Sehouli, Prof.Dr.       Jalid.Sehouli@charite.de   
Contact: Ioana Braicu, Dr.    +49 30 450 564 ext 002    ioana@braicu.de   
University Medical Center Freiburg Recruiting
Freiburg, Germany, 79106
Contact: Annette Hasenburg, Prof. Dr.    +49 761 270 ext 29440    annette.hasenburg@uniklinik-freiburg.de   
Contact: Michaela Bossart, Dr.    +49 761 270 ext 30250    michaela.bossart@uniklinik-freiburg.de   
University Clinic of Ruhr University Bochum Recruiting
Herne, Germany, 44626
Contact: Clemens B Tempfer, Prof.Dr.PhD.       clemens.tempfer@marienhospital-herne.de   
Contact: Günther Rezniczek, Dr.    +49 2323 499 ext 1058    guenther.rezniczek@rub.de   
Italy
European Institute of Oncology, Division of Gynecologic Oncology, Unit of Preventive Gynecology Recruiting
Milan, Italy, 20100
Contact: Michele Peiretti    +36 2 57489543    michele.peiretti@ieo.it   
United Kingdom
Imperial College London - Faculty of Medicine, Dpt. of Surgery & Cancer Recruiting
London, United Kingdom, SW7 2AZ
Contact: Hani Gabra, Prof.Dr.    +44 (0)20 3313 ext 5828    h.gabra@imperial.ac.uk   
Contact: Sarah Blagden, Dr.PhD    +44 (0)208 383 ext 4661    s.blagden@imperial.ac.uk   
Sponsors and Collaborators
Medical University of Vienna
Investigators
Principal Investigator: Robert Zeillinger, Prof.Dr. Medical University Vienna, Dptm. of Obstetrics & Gynaecology
  More Information

Additional Information:
Publications:

Responsible Party: Univ.Prof.Dr. Robert Zeillinger, Prof. Dr., Medical University of Vienna
ClinicalTrials.gov Identifier: NCT01763125     History of Changes
Other Study ID Numbers: EK 366/2003
Study First Received: January 4, 2013
Last Updated: November 14, 2013
Health Authority: Austria: Ethikkommission

Keywords provided by Medical University of Vienna:
Breast cancer
Ovarian cancer
Endometrium carcinoma
Cervix carcinoma,
Mamma carcinoma,
Prostata carcinoma
Colon carcinoma
Rectal carcinoma
Bronchus carcinoma
NSCLC & SCLC (Non Small Cell Lung Cancer & Small Cell Lung Cancer))
Prostate carcinoma

Additional relevant MeSH terms:
Neoplasms
Breast Neoplasms
Colorectal Neoplasms
Lung Neoplasms
Ovarian Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms
Lung Diseases
Respiratory Tract Diseases
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Genital Neoplasms, Female
Urogenital Neoplasms
Endocrine System Diseases
Gonadal Disorders

ClinicalTrials.gov processed this record on September 18, 2014