Longterm Follow-up After Remote Ischemic Preconditioning for Prevention of Contrast-induced Nephropathy (RenProLong)
Remote ischemic preconditioning reduces the incidence of contrast-induced acute kidney injury in patients undergoing elective coronary angiography. This study was designed to acquire long-term data of initially randomized patients in the RenPro Trial.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Remote Preconditioning for Contrast-Induced Acute Kidney Injury: Long-Term Follow up (RenPro Longterm)|
- MACCE [ Time Frame: 1 Year ] [ Designated as safety issue: Yes ]
Major Adverse Cardiac and Cerebrovascular Events (Combined primary endpoint):
All-cause mortality, cardiovascular mortality, rehospitalization, stroke, myocardial infarction, hemodialysis
- Renal function [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]changes of serum creatinine, eGFR, NGAL and cystatin C compared to baseline in both groups.
|Study Start Date:||July 2012|
|Estimated Study Completion Date:||January 2013|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Subjects with impaired renal function
Subjects with baseline impaired renal function undergoing cardiac catheterization with contrast-medium exposure
Other: Ischemic preconditioning
Subjects received ischemic preconditioning previous to cardiac catheterization
Data of the RenPro Trial has been already published. In the present study data of longterm follow up are collected.