GLOBAL Clinical Study
The GLOBAL study is an international multi-center, prospective study designed to enroll up to 10,000 consecutive eligible subjects who are clinically referred for coronary CT angiography for assessment of suspected coronary artery disease (CAD).
The purpose of the study is to perform extensive biomarker analysis of atherosclerosis in patients phenotyped using advanced imaging modalities of atherosclerosis.
Coronary Artery Disease
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Genetic Loci and the Burden of Atherosclerotic Lesions|
- Genome-Wide Association [ Time Frame: Baseline ] [ Designated as safety issue: No ]The primary analysis will be a genome-wide association analysis, to determine candidate genes and markers underlying coronary artery disease.
Biospecimen Retention: Samples With DNA
Whole blood, serum, plasma, buffy coat and RNA PAXgene
|Study Start Date:||December 2012|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||July 2014 (Final data collection date for primary outcome measure)|
|Subjects with CAD|
|Subjects without CAD|
|Contact: Brad Brown, MS||(804) email@example.com|
|Contact: Jeremy Moyer, MS||(610) firstname.lastname@example.org|
|United States, Kansas|
|Midwest Cardiology Associates||Recruiting|
|Overland Park, Kansas, United States, 66209|
|Semmelweis University||Not yet recruiting|
|Study Director:||Szilard Voros, MD||Global Genomics Group, LLC|