The Learning and Memory of the Experience of Pain

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2014 by Massachusetts General Hospital
Sponsor:
Information provided by (Responsible Party):
Jian Kong, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT01731314
First received: November 16, 2012
Last updated: March 25, 2014
Last verified: March 2014
  Purpose

This study investigates the learning and memory of pain.


Condition Intervention
Pain
Behavioral: Learning and Memory of Pain

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)

Resource links provided by NLM:


Further study details as provided by Massachusetts General Hospital:

Estimated Enrollment: 60
Study Start Date: January 2013
Estimated Study Completion Date: December 2016
Estimated Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. Male and female healthy volunteers.
  2. 18-65 years of age.
  3. Right-handed.
  4. Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

Exclusion Criteria:

  1. Any previous experience with conditioned analgesia/hyperalgesia paradigms.
  2. Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
  3. Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
  4. Instability of responses to experimental heat pain
  5. Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
  6. Peripheral neuropathy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01731314

Contacts
Contact: Jacky Yu 617-643-7946

Locations
United States, Massachusetts
MGH East Campus, 149 13th St. Recruiting
Charlestown, Massachusetts, United States, 02129
Contact: Jacky Yu         
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

No publications provided

Responsible Party: Jian Kong, MS, MD, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT01731314     History of Changes
Other Study ID Numbers: 2012P002386
Study First Received: November 16, 2012
Last Updated: March 25, 2014
Health Authority: United States: Institutional Review Board

ClinicalTrials.gov processed this record on October 19, 2014