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The MURDOCK Study Registry and Biorepository Horizon 1.5

This study is currently recruiting participants.
Verified May 2013 by Duke University
Sponsor:
Information provided by (Responsible Party):
Duke University
ClinicalTrials.gov Identifier:
NCT01708408
First received: October 15, 2012
Last updated: June 14, 2013
Last verified: May 2013
History of Changes
  Purpose

The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.


Condition Intervention
Chronic Disease
Healthy Volunteers
 Genetic: Biomarker studies

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis The MURDOCK Study Registry and Biorepository Horizon 1.5

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Duke University:

Biospecimen Retention:   Samples With DNA

Blood, 50 mL (whole blood, plasma, serum, buffy coat, PAXgene); Urine, 36 mL


Estimated Enrollment: 50000
Study Start Date: February 2009
Estimated Study Completion Date: December 2018
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
community Genetic: Biomarker studies

Detailed Description:

The MURDOCK Study Community Registry and Biorepository's activities include enrolling approximately 50,000 participants who live in Cabarrus County and/or Kannapolis, North Carolina. Participants must consent to (1) use of the data provided by the participant through completion of the Participant Registry Questionnaire for epidemiologic population characterization, (2) annual contact to update their MURDOCK Horizon 1.5 database record, (3) release of their medical information, including but not limited to demographic information, problem lists, medications, social and family history, and results of laboratory and other testing modalities from pre-existing paper or electronic health records or electronic health records that may become available in the future, (4) provision of a blood and urine sample, and (5) contact up to four times/year to request participation in additional research studies.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

The Community Registry and Biorepository is designed to create a community registry and biorepository populated by approximately 50,000 residents of Cabarrus County and/or the city of Kannapolis in North Carolina.

Criteria

Inclusion Criteria:

  1. A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) for 6 or more months of the year
  2. At least 18 years of age
  3. Able to understand and give written informed consent, or have a legal guardian or caregiver present to give informed consent by proxy (assent from a participant between ages 12-18 will be obtained when their parent or legal guardian consents on their behalf).
  4. Willing and able to participate in all 5 components of the registry and biorepository as described above in Section III

Exclusion Criteria:

1. There are no exclusions to participation if all inclusion criteria have been met.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01708408

Contacts
Contact: Leah Bouk 704-250-5856 leah.bouk@duke.edu
Contact: Perla Nunes 704-250-5858 perla.nunes@duke.edu

Locations
United States, North Carolina
Duke Translational Medicine Institute-MURDOCK Study Recruiting
Kannapolis, North Carolina, United States, 28081
Contact: Ashley Dunham, MSPH, PhD     704-250-5850     ashley.dunham@duke.edu    
Contact: Leah Bouk     704-250-5856     leah.bouk@duke.edu    
Principal Investigator: L. Kristin Newby, MD, MHS            
Sponsors and Collaborators
Duke University
Investigators
Principal Investigator: Robert M Califf, MD Duke University
  More Information

Additional Information:
MURDOCK Study website  This link exits the ClinicalTrials.gov site

Publications:

Responsible Party: Duke University
ClinicalTrials.gov Identifier: NCT01708408     History of Changes
Other Study ID Numbers: Pro00011196
Study First Received: October 15, 2012
Last Updated: June 14, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by Duke University:
electronic health records
biorepository
biobank
registry
community
biospecimens
 volunteers
chronic disease
longitudinal
blood
follow-up

Additional relevant MeSH terms:
Chronic Disease
Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on June 18, 2013