Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)
The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent.
The hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)|
- Volume of carbon dioxide rebreathing from an anesthetic gas reflector [ Time Frame: 2 hours ] [ Designated as safety issue: No ]Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.
- Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector. [ Time Frame: 2 hours ] [ Designated as safety issue: No ]Changes of tidal volume required to maintain constant alveolar ventilation will be assessed by continuous measurement of exhaled tidal carbon dioxide volume, the latter to be maintained at a constant value.
|Study Start Date:||September 2012|
|Estimated Study Completion Date:||April 2014|
|Estimated Primary Completion Date:||March 2014 (Final data collection date for primary outcome measure)|
Experimental: Inhaled anaesthetic agent
The group where the investigators adds inhaled anaesthetic agent when using the anaesthetic gas reflector (AnaConda).
|Other: Inhaled anaesthetic agent|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01699802
|Contact: Gunnar Malmkvist, M.D. Ph.D.||+46 46 firstname.lastname@example.org|
|Skane University Hospital Lund, Cardiothoracic Intensive Care||Recruiting|
|Lund, Sweden, SE-221 85|
|Contact: Louise C Walther Sturesson, M.D. +46 46 171953 email@example.com|
|Principal Investigator:||Mikael Bodelsson, Professor||Divison of Surgery, Department of Anaesthesia, Skane University Hospital, Lund, Sweden|