Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya. In Kenya very young children are given drinking water or water is used in reconstitution of their food. We hypothesize that ceramic water filters will remove Cryptosporidium from drinking water reducing infection in infants.
Other: Ceramic water filter
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:||Pilot Intervention Trial of Ceramic Water Filters to Reduce the Burden of Cryptosporidium in Household Drinking Water in Rural Kenya.|
- Longitudinal diarrhea prevalence [ Time Frame: 6 months ] [ Designated as safety issue: No ]The primary outcome measure is the longitudinal prevalence of diarrheal disease.
|Study Start Date:||February 2013|
|Estimated Primary Completion Date:||August 2013 (Final data collection date for primary outcome measure)|
Experimental: Intervention Arm
Households with a child 4-10 months old will receive a Cera Maji ceramic water filter for treatment of drinking water.
Other: Ceramic water filter
In total, 120 households with a child 4-10 months old will receive a Cera Maji ceramic water filter for treatment of drinking water at initial entry into the study (intervention group), and 120 households with a child 4-10 months old at initial entry into the study will not receive a ceramic water filter (control group). The study duration will be 6 months. All households in the control group will receive a Cera Maji ceramic water filter when the study ends.
Other Name: Cera Maji ceramic water filter
No Intervention: Control Arm
Households with a child 4-10 months old at initial entry into the study will not receive a ceramic water filter (control group). The study duration will be 6 months. All households in the control group will receive a Cera Maji ceramic water filter when the study ends.
Diarrhea is a major cause of illness among children in Africa. Cryptosporidium is a protozoan waterborne diarrheal pathogen resistant to chlorine. Ceramic filters are effective at improving drinking water quality, including removal of protozoa. In a recent preliminary analysis of >22,000 children <5 years enrolled in the Global Enterics Multi-Center Study (GEMS) case-control study of moderate-to-severe diarrhea, Cryptosporidium was identified as a leading cause of diarrhea in infants across all four participating African sites. This pilot is the first Cryptosporidium specific intervention trial of household ceramic water filters to reduce the burden of cryptosporidiosis acquired through drinking water in rural Kenya.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01695304
|Contact: Ciara O'Reilly, PhDemail@example.com|
|Contact: Eric Mintz, MD, MPHfirstname.lastname@example.org|
|Not yet recruiting|
|Principal Investigator: Richard Omore, MPH|
|Sub-Investigator: Benjamin Ochieng, MSc|
|Sub-Investigator: Peter Jaron|
|Principal Investigator:||Eric Mintz, MD, MPH||Centers for Disease Control and Prevention|