OPtimal Type 2 dIabetes Management Including Benchmarking and Standard Treatment in CEEMEA (OPTIMISE)

This study is currently recruiting participants.
Verified April 2013 by AstraZeneca
Sponsor:
Information provided by (Responsible Party):
AstraZeneca
ClinicalTrials.gov Identifier:
NCT01694758
First received: September 25, 2012
Last updated: April 19, 2013
Last verified: April 2013
  Purpose

OPTIMISE-CEEMEA is a multinational, multi-centre, observational, prospective study which will include patients suffering from diabetes type 2, treated or untreated, insulin dependent or not insulin dependent.

In this study we aim to explore at a primary care level whether the use of benchmarking against a set of guideline-based reference values on a patient basis, may improve quality of patient care, in particular control of diabetes, lipids and blood pressure.


Condition
Diabetes Mellitus, Non-Insulin-Dependent

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: OPtimal Type 2 dIabetes Management Including Benchmarking and Standard Treatment in CEEMEA (OPTIMISE)

Resource links provided by NLM:


Further study details as provided by AstraZeneca:

Primary Outcome Measures:
  • Percentage of patients in the benchmarking group achieving pre-set targets for HbA1c1 [ Time Frame: after 12 months of follow-up ] [ Designated as safety issue: No ]
    To investigate whether the use of benchmarking could improve quality of patient care, in particular the control of diabetes, lipids and blood pressure, expressed as the percentage of patients in the benchmarking group achieving pre-set targets for HbA1c1


Secondary Outcome Measures:
  • Quality of patient care improvement, in particular the control of diabetes, lipids and blood pressure [ Time Frame: after 12 months of follow-up versus baseline ] [ Designated as safety issue: No ]
    To investigate whether the use of benchmarking could improve quality of patient care, in particular the control of diabetes, lipids and blood pressure

  • Markers of preventive screening [ Time Frame: after 12 months of follow-up versus baseline ] [ Designated as safety issue: No ]
    To follow up evolution markers of preventive screening; retinopathy, neuropathy, dietary counseling, smoking habits, BMI, waist circumference, physical activity

  • The LDL cholesterol parameter of the primary and secondary objectives according to ATP III guidelines [ Time Frame: after 12 months of follow-up versus baseline ] [ Designated as safety issue: No ]
    To investigate the LDL cholesterol parameter of the primary and secondary objectives according to ATP III guidelines


Estimated Enrollment: 500
Study Start Date: November 2012
Estimated Study Completion Date: April 2014
Estimated Primary Completion Date: January 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
Patients with diabetes type 2

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with diabetes type 2

Criteria

Inclusion Criteria:

  • Subjects suffering from diabetes type 2,
  • treated or untreated,
  • insulin dependent or not insulin dependent Able to read and send SMS (if SMS applicable)

Exclusion Criteria:

  • Type 1 diabetes Pregnancy diabetes
  • Hospitalization at the moment of enrollment in the study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01694758

Contacts
Contact: AstraZeneca Clinical Study Information informatie.medicala@astrazeneca.com

Locations
Romania
Research Site Recruiting
Alexandria, Romania
Research Site Recruiting
Brasov, Romania
Research Site Recruiting
Bucuresti, Romania
Research Site Recruiting
Cluj, Romania
Research Site Recruiting
Constanta, Romania
Research Site Not yet recruiting
Craiova, Romania
Research Site Recruiting
Galati, Romania
Research Site Recruiting
Giurgiu, Romania
Research Site Recruiting
Iasi, Romania
Research Site Recruiting
Oradea, Romania
Research Site Recruiting
Pitesti, Romania
Research Site Not yet recruiting
Ploiesti, Romania
Research Site Recruiting
Satu Mare, Romania
Research Site Recruiting
Tg Jiu, Romania
Research Site Recruiting
Tg Mures, Romania
Research Site Recruiting
Timisoara, Romania
Sponsors and Collaborators
AstraZeneca
Investigators
Principal Investigator: Dan Isacoff, ASSOC. PROF. University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
  More Information

No publications provided

Responsible Party: AstraZeneca
ClinicalTrials.gov Identifier: NCT01694758     History of Changes
Other Study ID Numbers: NIS-CME-XXX-2012/1
Study First Received: September 25, 2012
Last Updated: April 19, 2013
Health Authority: Romania: National Medicine and Medical Devices Agency

Keywords provided by AstraZeneca:
Benchmarking could improve quality of patient care
ESC and ATP III Guidelines

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases

ClinicalTrials.gov processed this record on May 16, 2013