Use of a Novel Neuroplasticity-based Neurobehavioral Intervention for PTSD

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2014 by Stanford University
Sponsor:
Information provided by (Responsible Party):
Stanford University
ClinicalTrials.gov Identifier:
NCT01694316
First received: September 24, 2012
Last updated: March 3, 2014
Last verified: March 2014
  Purpose

The present study will explore the effectiveness of a computer based neurobehavioral intervention in alleviating symptoms and improving emotion regulation in veteran's with PTSD. It will increase understanding of psychopathology at a neural-circuit level and aid development of new non-pharmacological treatment for PTSD. The study is managed by the Etkin Lab at Stanford University in California, but participants from the entire US are welcome to participate as the study is delivered online.


Condition Intervention
Anxiety
Depression
Behavioral: Computerized Neurobehavioral Intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Basic Science
Official Title: Use of a Novel Neuroplasticity-based Neurobehavioral Intervention for PTSD - A Nationwide, Online Study

Resource links provided by NLM:


Further study details as provided by Stanford University:

Primary Outcome Measures:
  • Emotional conflict adaptation - EEG imaging and behavioral [ Time Frame: 3-month ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • PTSD- clinician assessed and self-report symptoms [ Time Frame: 3-month ] [ Designated as safety issue: No ]

Estimated Enrollment: 40
Study Start Date: September 2012
Estimated Study Completion Date: September 2016
Estimated Primary Completion Date: September 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Engaging in Computerized tasks
Participants will log into a personalized website and engage in computerized tasks online.
Behavioral: Computerized Neurobehavioral Intervention
Targeted, computerized interventions completed from the participants' own home on a computer.
Experimental: Neurobehavioral computerized tasks
Participants will log into a personalized website and engage in computerized tasks online.
Behavioral: Computerized Neurobehavioral Intervention
Targeted, computerized interventions completed from the participants' own home on a computer.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • current PTSD
  • internet access
  • veteran of the US military

Exclusion Criteria:

  • lifetime psychotic disorder,
  • past-year substance dependence
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01694316

Contacts
Contact: Jurema K Gobena 650-725-9510 psychiatry@stanford.edu

Locations
United States, California
Stanford University, Department of Psychiatry and Behavioral Sciences Recruiting
Stanford, California, United States
Principal Investigator: Amit Etkin, MD PhD         
Sponsors and Collaborators
Stanford University
  More Information

Additional Information:
No publications provided

Responsible Party: Stanford University
ClinicalTrials.gov Identifier: NCT01694316     History of Changes
Other Study ID Numbers: IRB-24890
Study First Received: September 24, 2012
Last Updated: March 3, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by Stanford University:
Computerized neurobehavioral intervention

Additional relevant MeSH terms:
Depression
Behavioral Symptoms

ClinicalTrials.gov processed this record on October 23, 2014