Pseudoexfoliation and Chronic Kidney Disease
Background: Pseudoexfoliation (PEX) is characterised by the deposition of fibrillar material in an eye structures and many other parts of the body including kidneys and blood vessels. As both PEX and chronic kidney disease (CKD) are associated with oxidative stress and endothelial dysfunction we studied if the risk of PEX was increased in patients with CKD.
Methods: Patients over age 40 with the diagnosis of CKD were included in the study. Chronic kidney disease was diagnosed as decreased glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m². Study groups were arranged as group 1 consisting of HD receiving patients, group 2 consisting of stage 1-4 CKD patients and group 3 consisting of patients with normal kidney functions (control group). Demographic properties and the rate of PEX were evaluated and compaired between the groups.
Chronic Kidney Disease
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Relationship Between Pseudoexfoliation and Chronic Kidney Disease|
- Prevalance of pseudoexfoliation in patients with chronic kidney disease [ Time Frame: 7 months ] [ Designated as safety issue: No ]
|Study Start Date:||October 2011|
|Study Completion Date:||April 2012|
Patients with stage 5 chronic kidney disease undergoing haemodialysis
Chronic kidney disease patients
Stage 1-4 Chronic kidney disease patients
Patients with normal renal functions