Grass Sensitisation and Allergic Rhinitis in Thai Patients
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
Allergy to Grass Pollen
Allergic Rhinitis Due to Weed Pollens
|Official Title:||The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients|
|Study Start Date:||October 2012|
|Estimated Study Completion Date:||March 2014|
|Estimated Primary Completion Date:||November 2013 (Final data collection date for primary outcome measure)|
Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition
serum specific IgE binds to grass extract by immunoblot
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01686022
|Contact: Punchama Pacharn, MD||6624197000 ext firstname.lastname@example.org|
|Contact: Chaweewan Bunnag, MD||6624197000 ext email@example.com|
|Bangkoknoi, Bangkok, Thailand, 10700|
|Principal Investigator:||Punchama Pacharn, MD||Mahidol University|