Evaluation of Brain MRI and Clinical Characteristics of Adolescents With Bipolar Disorder and Children of Parents With Bipolar Disorder
Genetic transition is important in the etiology of bipolar disorder (BD). So, evaluation of children of BD parents and diagnosed with and BD children whether or not brain has affected zones. These groups were compared to healthy controls and whether or not the mental health of children is influenced will be evaluated by the clinical investigation.
|Study Design:||Time Perspective: Prospective|
|Study Start Date:||July 2011|
|Estimated Study Completion Date:||June 2013|
|Estimated Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
Children with BD, (20 children) 12-18 year-old who agreed to participate in the study will be established.
Twenty healthy children of 12-18 years old who have mothers and/or fathers who previously assessed by an adult psychiatrist and diagnosed as BD according to DSM-IV diagnostic criteria, and who agreed to participate in the study. The age and gender of the groups will be matched.
Healthy control group
Twenty participants between the ages of 12-18 who agree to participate in the study and whose family members do not have BD. The age and the gender of the groups will be matched.
MRI studies in children at risk of BD, our understanding of the neurobiology of BD and abnormalities in the studied regions, regions that predispose to the development of our understanding of PBB will shed light on the etiology of the disorder. In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated. Since there is few studies that evaluate these three groups, there is a need to increase our knowledge on this issue.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01678989
|Contact: Seher Akbas||09003623121919 ext email@example.com|
|Contact: Gökhan Sarisoy||09003623121910 ext firstname.lastname@example.org|
|Ondokuz Mayis University Medical Faculty Department of Child and Adolescent Psychiatry||Recruiting|
|Samsun, Turkey, 55139|
|Contact: Seher Akbas 00903623121919 ext 3128 email@example.com|
|Principal Investigator: Seher Akbas|