Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis) (BIOSEPSIS)
Recruitment status was Recruiting
Septic shock is a frequent pathology responsible for over 30000 deaths/year in France. Its outcome has not been improved despite the knowledge on inflammatory processes; a reason for these lack of results may lay on the lack of data on the precise dynamics of inflammatory and anti-inflammatory cascades and their consequences. We intend to achieve accurate monitoring of the inflammatory process on a small group of non-immunocompromised patients. Our goal is to obtain quality data, repeated over time, by limiting the technical variability.
Immunocompetent Patient on Septic Shock
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis)|
- Evolutive profile of the inflammatory response during septic shock [ Time Frame: Hospitalisation in ICU ] [ Designated as safety issue: No ]
- Research for early prognosis factors [ Time Frame: Hospitalisation in ICU ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
hormons, inflammatory markers, vitamines recovered from the patients serum.
|Study Start Date:||September 2009|
|Estimated Study Completion Date:||June 2013|
|Estimated Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
The aim is to obtain precise data on the dynamics of cytokines, oxydative stress and hormonal response on immunocompetent adults during septic shock.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01668329
|Contact: TIMSIT Jean François, PU/PH||0476768779||JFTimsit@chu-grenoble.fr|
|University Hospital Grenoble||Recruiting|
|Grenoble, France, 38043|
|Contact: TIMSIT Jean Francois, PU/PH 0476768779 JFTimsit@chu-grenoble.fr|
|Contact: TOURNEGROS Caroline, ARC 0476767109 CTournegros@chu-grenoble.fr|
|Principal Investigator:||TIMSIT Jean FRANCOIS, PU/PH||University Hospital, Grenoble|